Results 361 to 370 of about 170,603 (392)
Some of the next articles are maybe not open access.
Culture of Immortalized Chondrocytes and Their Use As Models of Chondrocyte Function
2004Immortalization of chondrocytes increases life span and proliferative capacity but does not necessarily stabilize the differentiated phenotype. Expansion of chondrocyte cell lines in continuous monolayer culture may result in the loss of phenotype, particularly if high cell density is not maintained. This chapter describes strategies for maintaining or
openaire +3 more sources
Journal of Cellular Physiology, 1994
AbstractThe objectives of this study were to establish a growth factor response profile for adult human articular chondrocytes, to determine whether this is unique for chondrocytes or influenced by the differentiation status of the cells, and to characterize growth factor interactions.
Pierre-André Guerne +2 more
openaire +3 more sources
AbstractThe objectives of this study were to establish a growth factor response profile for adult human articular chondrocytes, to determine whether this is unique for chondrocytes or influenced by the differentiation status of the cells, and to characterize growth factor interactions.
Pierre-André Guerne +2 more
openaire +3 more sources
Transplantation of Isolated Chondrocytes
Clinical Orthopaedics and Related Research, 1991Intramuscular transplantation of isolated syngeneic chondrocytes from hyaline and elastic cartilage results in formation of cartilage with various degrees of similarity to the original tissue. Cells from cartilage with a simple structure, such as nasal septal cartilage, form islands of tissue with flattened chondrocytes at the periphery and more ...
openaire +2 more sources
Chondrocyte Proliferation and Differentiation
2011The skeletal elements of the axial and appendicular skeleton are preformed as cartilage templates by a mechanism called endochondral ossification. During this process, a cartilage template is formed in which chondrocytes proliferate and differentiate into hypertrophic chondrocytes and are gradually replaced by bone.
Manuela Wuelling, Andrea Vortkamp
openaire +3 more sources
Autologous Chondrocyte Transplantation
Clinical Orthopaedics and Related Research, 1999The intrinsic capacity of cartilage to repair chondral injuries is poor. Different techniques to induce cartilage repair with the use of extrinsic chondrogeneic cell sources have been explored in experimental models. Cells can be harvested autologously or as allografts from a healthy part of the donor tissue, isolated, expanded in vitro, and finally ...
openaire +3 more sources
2005
We have little systematic information to explain the heterogeneity of cartilage and bones as tissue, or of chondrocytes and osteocytes as differentiated cells. Does heterogeneity originate in the initial determination or setting-aside of precursor cells for chondrogenesis or is it an aspect of later stages of chondrocyte differentiation?
openaire +3 more sources
We have little systematic information to explain the heterogeneity of cartilage and bones as tissue, or of chondrocytes and osteocytes as differentiated cells. Does heterogeneity originate in the initial determination or setting-aside of precursor cells for chondrogenesis or is it an aspect of later stages of chondrocyte differentiation?
openaire +3 more sources
Autologous Chondrocyte Transplantation: Chondrocyte Culturing and Clinical Aspects
1998The high clinical and socio-economical impact of cartilage defects and chondral degeneration is well known. After trauma or without known ethiology, young patients often suffer from pain and loss of function leading to a decrease in physical activity and, which is more severe, to long-term disability and unemployment.
Erggelet, Christoph +1 more
openaire +3 more sources
Chondrocyte dedifferentiation and osteoarthritis (OA).
Biochemical Pharmacology, 2019E. Charlier +7 more
semanticscholar +1 more source
The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis
Ageing Research Reviews, 2021Ziji Zhang, Puyi Sheng, Ali Mobasheri
exaly