Results 121 to 130 of about 222,465 (345)

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri, Renata Maia, Pei Zhang, Liliana Agresti, Jelmer Sjollema, Mohammad‐Ali Shahbazi, Hélder A. Santos   +6 more
wiley   +1 more source

A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering

Advanced Healthcare Materials, EarlyView.
In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng, Huajian Chen, Chengyu Lu, Tianjiao Zeng, Man Wang, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen   +8 more
wiley   +1 more source

AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration

Advanced Healthcare Materials, EarlyView.
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer, Muhammad Hassan Razzaq, Mehmet Fatih Aycan, Yogendra Kumar Mishra   +3 more
wiley   +1 more source

Platelet Rich Plasma Combined with Collagen Matrix Promotes Chondrocyte Regeneration in Arthritis and the Effect of Nanoparticles on Oxygen Free Radicals [PDF]

, 2022
Qiumin Li
openalex   +1 more source

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain

Arthritis Research & Therapy, 2014
IntroductionNerve growth factor (NGF) level is increased in osteoarthritis (OA) joints and is involved in pain associated with OA. Stimuli responsible for NGF stimulation in chondrocytes are unknown.
É. Pecchi, S. Priam, M. Gosset, A. Pigenet, L. Sudre, Marie-Charlotte Laiguillon, F. Berenbaum, X. Houard   +7 more
semanticscholar   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency

JCI Insight
The resting zone of the postnatal growth plate is organized by slow-cycling chondrocytes expressing parathyroid hormone-related protein (PTHrP), which include a subgroup of skeletal stem cells that contribute to the formation of columnar chondrocytes ...
Shion Orikasa, Yuki Matsushita, Hiroaki Manabe, Michael Fogge, Zachary Lee, Koji Mizuhashi, Naoko Sakagami, Wanida Ono, Noriaki Ono   +8 more
doaj   +1 more source

Cytokine Receptor-like Factor 1 (CRLF1) and Its Role in Osteochondral Repair

Cells
Background: Since cytokine receptor-like factor 1 (CRLF1) has been implicated in tissue regeneration, we hypothesized that CRLF1 released by mesenchymal stem cells can promote the repair of osteochondral defects.
Fenglin Zhang, Andrew J. Clair, John F. Dankert, You Jin Lee, Kirk A. Campbell, Thorsten Kirsch   +5 more
doaj   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source