Results 101 to 110 of about 231,673 (393)

The ability of H2O2 to induce differentiation of human mesenchymal stem cells into chondrocytes [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim:Cartilagedisordersmaydeterioratefollowingoxidative stress injuriesaffectingmature chondrocytes. Meantime, mesenchymal stem cells (MSCs)candifferentiateinto chondrocytes in thepresence ofoxidative conditionsandact as ...
Goudarzi F, Mohammadalipour A, Bahabadi M, Moradi M.N, Sarveazad A, Goodarzi M.T, Khodadadi I   +6 more
doaj   +1 more source

Platelet Rich Plasma Combined with Collagen Matrix Promotes Chondrocyte Regeneration in Arthritis and the Effect of Nanoparticles on Oxygen Free Radicals [PDF]

, 2022
Qiumin Li, J Dequeker, L Mokassa, J Aerssens, S Boonen, T Oegema, R Carpenter, F Hofmeister, R Thompson, Y Cheng, C Macera, D Davis, B Ainsworth, S Blair, G Zhen, C Wen, X Jia, Y Li, J Crane, S Mears, E Blaney Davidson, D Van, M Weinberger, W Tierney, P Booher, S Hiner, Baselga Garc A-Escudero, Miguel Jaime, Trillos Hernndez, Pedro, A Shervin, E Livne, Andr Snchez, P Sheridan, L Kupp, A Pradeep, S Pai, G Garg, P Devi, S Shetty, M Takikawa, S Nakamura, S Nakamura, M Ishirara, T Kiyosawa, L Chamberlain, I Yannas, H Hsu, G Strichartz, M Spector, P Van Wachem, M Van Luyn, D Ponte, S Miranda, M Costa, Natlia Rebouas, T Mrcia, Ramos, N Alencar, G Hoareau, K Jandrey, J Burges, D Bremer, F Tablin   +63 more
openalex   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

The use of commercially available adhesive tapes to preserve cartilage and bone tissue integrity during cryosectioning

BioTechniques, 2018
The use of fluorescent tags to monitor protein expression and to lineage-trace cells has become a standard complement to standard histological techniques in the fields of embryology, pathology and regenerative medicine.
Maxwell A Serowoky, Divya D Patel, Jason W Hsieh, Francesca V Mariani   +3 more
doaj   +1 more source

Histological features of the distal third metacarpal bone in thoroughbred racehorses, with and without lateral condylar fractures [PDF]

, 2017
A detailed histopathological study of the distal third metacarpal bone of Thoroughbred racehorses was undertaken to characterize lesions observed previously on magnetic resonance imaging (MRI).
Blunden, A.S., Chang, Y.M., Murray, R.C., Parkin, T.D.H., Pinilla, M.J., Tranquille, C.A.   +5 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

3D Culture of Chondrocytes in Gelatin Hydrogels with Different Stiffness

Polymers, 2016
Gelatin hydrogels can mimic the microenvironments of natural tissues and encapsulate cells homogeneously, which makes them attractive for cartilage tissue engineering.
Xiaomeng Li, Shangwu Chen, Jingchao Li, Xinlong Wang, Jing Zhang, N. Kawazoe, Guoping Chen   +6 more
semanticscholar   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis

Genes and Diseases
Chondrocyte is considered the only cell type in cartilage. However, the cell heterogeneity of chondrocytes in human articular cartilage is still not well defined, which hinders our understanding of the pathogenesis of osteoarthritis (OA).
Changyuan Huang, Bin Zeng, Bo Zhou, Guanming Chen, Qi Zhang, Wenhong Hou, Guozhi Xiao, Li Duan, Ni Hong, Wenfei Jin   +9 more
doaj   +1 more source

Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium. [PDF]

, 1994
Epiphyseal chondrocytes cultured in a medium containing 10% serum may be maintained as three dimensional aggregates and differentiate terminally into hypertrophic cells.
Ballock, RT, Reddi, AH
core