Results 81 to 90 of about 231,673 (393)

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Auricle shaping using 3D printing and autologous diced cartilage. [PDF]

, 2019
ObjectiveTo reconstruct the auricle using a porous, hollow, three-dimensional (3D)-printed mold and autologous diced cartilage mixed with platelet-rich plasma (PRP).MethodsMaterialise Magics v20.03 was used to design a 3D, porous, hollow auricle mold ...
Chen, Jia, Chen, Yong, He, Bin, Li, Qingfeng, Liao, Junlin, Qian, Li, Wang, Aijun, Xie, Hongju, Xu, Jiaqin, Zhou, Jianda   +9 more
core   +1 more source

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

Advanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu, Mengsi Zhan, Haoyu Huang, Jianhong Wang, Cheng Ni, Xiaojun Zhou, Hannah Küttner, Cong Song, Xiangyang Shi, Andrij Pich   +9 more
wiley   +1 more source

Use of autologous adipose-derived mesenchymal stem cells for creation of laryngeal cartilage [PDF]

, 2017
OBJECTIVES/HYPOTHESIS: Adipose-derived mesenchymal stem cells (ASCs) are an exciting potential cell source for tissue engineering because cells can be derived from the simple excision of autologous fat.
Brookes, Sarah, Halum, Stacey, Parker, Noah, Voytik-Harbin, Sherry, Wallace, Joseph, Zhang, Hongji, Zhang, Lujuan   +6 more
core   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

Advanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro, Mario González‐Quintas, Mónica Fernández‐Arias, Jesús del Val, Félix Quintero, Rafael Comesaña, Fernando Lusquiños, Julian R. Jones, Juan Pou   +8 more
wiley   +1 more source

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization [PDF]

, 2009
Initiation of mineralization during endochondral ossification is a multistep process and has been assumed to correlate with specific interactions of annexins A5 and A6 and collagens.
Anderson, Anja Niehoff, Balcerzak, Balcerzak, Belluoccio, Bent Brachvogel, Berendes, Blumbach, Brachvogel, Brachvogel, Brachvogel, Bradford, Budde, Christian Frie, Collett, Damazo, Daniele Belluoccio, DiCesare, Ernst Pöschl, Friedericke Pausch, Genge, Genge, Gerke, Girkontaite, Haut Donahue, Hawkins, Hazarika, Hikiji, Hofmann, Ivan Grskovic, John F Bateman, Julia Etich, Karsenty, Karsenty, Kim, Kirsch, Kirsch, Kirsch, Koopman, Kwan, Ling, Livak, Morgan, Murshed, Pfaffl, Rety, Romeis, Sabrina Rosenbaum, Schmitz, Srivastava, Srivastava, Stephen E Moss, Ursula Schlötzer-Schrehardt, Van Gelder, White   +54 more
core   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Redifferentiated Chondrocytes for the Repair of Articular Cartilage Lesions

Orthopaedic Journal of Sports Medicine, 2017
Objectives: Biological therapies such as autologous chondrocyte implantation which use serially passaged chondrocytes to repair cartilage defects, are often unsuccessful as they lead to the formation of fibrocartilage.
Vanessa Juliana Bianchi B.Sc., John S. Theodoropoulos MD, FRCSC, Rita Kandel M.D., David Backstein MEd, M.D., FRCSC   +3 more
doaj   +1 more source

Hyaluronic Acid Loaded with Cerium Oxide Nanoparticles as Antioxidant in Hydrogen Peroxide Induced Chondrocytes Injury: An In Vitro Osteoarthritis Model

Molecules, 2020
Osteoarthritis (OA) is the most common joint disease type and is accompanied by varying degrees of functional limitation. Both hyaluronic acid (HA) joint injections and pain relievers are efficient treatments for early-stage osteoarthritis.
Yi-Wen Lin, Chih-Hsiang Fang, Fan-Qi Meng, Cherng-Jyh Ke, Feng-Huei Lin   +4 more
doaj   +1 more source