Results 151 to 160 of about 171,876 (350)
Effects of anti-inflammatory drugs on matrix degradation of rabbit articular chondrocytes in vitro.
, 1986 K. Shimada +5 more
openalex +2 more sources
Roles of Interaction between CCN2 and Rab14 in Aggrecan Production by Chondrocytes [PDF]
, 2020 Mitsuhiro Hoshijima +6 more
openalex +1 more source
Advanced Science, EarlyView.ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu +9 more
wiley +1 more source
Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases
Advanced Science, EarlyView.Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh +17 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT SHOX gene haploinsufficiency is associated with Léri‐Weill dyschondrosteosis (LWD) or idiopathic short stature (ISS) and could be caused by the structural and point mutations in the coding region and by the deletions in SHOX gene regulatory sequences. The role of the duplications in regulatory sequences is ambivalent.
Valeriia Kopytko +3 more
wiley +1 more source
Modeling and Simulation of the Effects of Cyclic Loading on Articular Cartilage Lesion Formation
, 2013 We present a model of articular cartilage lesion formation to simulate the effects of cyclic loading. This model extends and modifies the reaction-diffusion-delay model by Graham et al.
Ayati, Bruce P. +5 more
core
A non‐interventional study to evaluate the safety and effectiveness of a biphasic, chondrocyte‐containing biomaterial (NOVOCART® 3D) in the treatment of localized full‐thickness cartilage defects or osteochondral lesions of the knee joint (NISANIK) [PDF]
Julia Elisabeth Lenz +11 more
openalex +1 more source
Active extrusion of Ca2+ from epiphysial chondrocytes of normal and rachitic chickens [PDF]
, 1982 María Eugenia Zanetti +3 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou +5 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu +6 more
wiley +1 more source