Results 171 to 180 of about 33,920 (248)

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

Minced cartilage implantation provides comparable outcomes to autologous chondrocyte implantation (ACI) for knee cartilage lesions: A matched‐pair analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare short‐term patient‐reported outcomes (PROMs) and revision rates between autologous hand‐minced cartilage implantation (MCI) and autologous chondrocyte implantation (ACI) for knee cartilage lesions. Methods All patients undergoing MCI or ACI at a single centre were retrospectively analysed from a prospectively maintained ...
Armin Runer, Louis Leuthard, Luisa Hoheisel, Vincent A. Stadelmann, Stefan Preiss, Gian M. Salzmann, Jakob Hax   +6 more
wiley   +1 more source

Gait alterations increase friction of degenerated articular cartilage: A tribological study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To investigate the effect of gait alterations associated with osteoarthritis (OA) on the frictional properties of porcine articular cartilage (AC) in intact and degenerative conditions. Methods Forty‐eight cylindrical AC samples were harvested from 12 porcine femur condyles and equally divided between four groups with n = 12 samples ...
Luisa de Roy, Graciosa Quelhas Teixeira, Maria Ahrens, Benjamin Mayer, Cornelia Horsch, Anita Ignatius, Andreas Martin Seitz   +6 more
wiley   +1 more source

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio, Ryosuke Kuroda, Yasuo Niki, Katsura Sugawara, Yasuyuki Ishibash   +4 more
wiley   +1 more source

Concomitant cartilage restoration does not demonstrate consistent additional clinical benefit in medial patellofemoral ligament reconstruction: A systematic review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This review specifically evaluates whether the presence of cartilage lesions, or their surgical treatment, modifies the clinical benefit of medial patellofemoral ligament (MPFL) reconstruction. Methods A systematic review was conducted following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines ...
Dave Osinachukwu Duru, Djamel Wade, Marc Daniel Bouchard, Prushoth Vivekanantha, Shahbaz S. Malik, Nathan Wm Skelley, Bryson P. Lesniak, Darren de Sa   +7 more
wiley   +1 more source

Revision rates are similar after surgical treatment of acute chondral and osteochondral injuries following patellar dislocation: A multicentre cohort study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Optimal treatment strategies for (osteo‐)chondral injuries following patellar dislocation remain unclear. This retrospective multicentre study aimed to compare outcomes between chondral and osteochondral lesions and to explore factors associated with revision surgery.
Andrea Maria Hediger, Thomas Lustenberger, Emanuel Francis Liechti, Pierre Hepp, Marie Samland, Ralf Henkelmann, Thomas Armin Schildhauer, Matthias Königshausen, Thomas Rosteius, Till Orla Klatte, Hendrik Fahlbusch, Johannes Zellner, Thomas Habereder, Christoph Kittl, Marion Laumann, Elmar Herbst, Thorben Briese, Tobias Johannes Gensior, Robert Roenick, Bastian Mester, Richard Glaab   +20 more
wiley   +1 more source

Comparative Effects of Photobiomodulation and Platelet‐Rich Plasma on Joint Repair in Rats With Knee Osteoarthritis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective This study aimed to evaluate whether the combination of photobiomodulation and platelet‐rich plasma therapy provides superior anti‐inflammatory and joint‐protective effects compared to individual treatments in an experimental model of osteoarthritis.
Anne Missrie, Gabriela Saab Sampaio, Vitória Gonzaga Acerbi, Fernando Anselmo, Ítalo Ribeiro Lemes, Ana Laura Martins de Andrade   +5 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source