Abstract Background Culture protocols need to yield 100 million equine synovial fluid (SF)‐derived mesenchymal stromal cells (SF‐MSCs) in around 3 weeks are needed, before these cells can be evaluated as agents of articular repair in clinical trials. Objectives To investigate mass culture of equine SF‐MSC culture protocols using nonwoven polyethylene ...
Miho Daniel Yoshitomi +5 more
wiley +1 more source
Acupotomy Ameliorates KOA Related Chondrocyte Premature Senescence Through YAP/FOXD1 Pathway
Yunxuan Ma,1,* Tingyao Hu,1,* Naigang Liu,2 Changqing Guo,1 Longfei Xing,3 Weiwei Ma,4 Yongqi Cui,1 Xilin Chen5 1School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department
Ma Y +7 more
doaj
Traditional Chinese medicine-derived monomers protect chondrocytes and delay osteoarthritis progression by regulating mitochondrial quality control. [PDF]
Yang X, Li Y.
europepmc +1 more source
Review of articular cartilage repair techniques and their application in the horse
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
Multi-omics and experimental evidence in human chondrocytes identify caspase-8 as a non-apoptotic regulator of inflammatory, senescent, and fibrotic signaling in osteoarthritis. [PDF]
Mei J +6 more
europepmc +1 more source
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé +6 more
wiley +1 more source
Jisheng Ran,* Chiyuan Ma,* Kai Xu,* Langhai Xu, Yuzhe He, Safwat Adel Abdo Moqbel, Pengfei Hu, Lifeng Jiang, Weiping Chen, Jiapeng Bao, Yan Xiong, Lidong Wu Department of Orthopedic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang ...
Xu L +11 more
core
Chondrocytes in fracture healing: A review of chondrocyte journey. [PDF]
Zhang T +8 more
europepmc +1 more source
Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel +7 more
wiley +1 more source
FGF9 attenuates osteoarthritis progression through the NRF2/GPX3 antioxidant axis. [PDF]
Lo YS +10 more
europepmc +1 more source

