Results 181 to 190 of about 97,024 (315)

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Eicosapentaenoic acid restores inflammation-induced changes in chondrocyte mechanics by suppressing the NF-κB p65/CD44 signaling pathway and attenuates osteoarthritis. [PDF]

Exp Mol Med
Yang Q, Wu J, Huang S, Zeng J, Jing Y, Wang Z, Zhang C, Wu Z, Liu S, Wang Z.   +9 more
europepmc   +1 more source

MODULATION DE L'EXPRESSION DE GENES DE COLLAGENE DANS DES CHONDROCYTES EPIPHYSAIRES DE LAPIN EN CULTURE [PDF]

, 1989
V. Nataf, L. Tsagris, Jacky Bonaventure, MT Corvol   +3 more
openalex   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Bromodomain and Extraterminal Protein Inhibition: A Novel Therapeutic Strategy in Arthritis. [PDF]

J Inflamm Res
Sheng W, Zhao J, Yu F, Wang D, Zeng H, Liu P.   +5 more
europepmc   +1 more source

Synthesis of Small Proteoglycans Substituted with Keratan Sulfate by Rabbit Articular Chondrocytes

, 1989
Anna Plaas, A L Ison, Jacqueline F. Ackland   +2 more
openalex   +1 more source

Programmatic regulation of macrophage polarization by HAp@MXene nanocomposites to promote bone repair

BMEMat, EarlyView.
HAp@MXene nanocomposites could achieve the programmed regulation of macrophage polarization. They first induce M1 polarization through magnetoelectric induction to combat infection. Subsequently, controlled Ca2+ release drives M2 polarization to promote tissue regeneration. This dual mechanism accelerates bone defect repair and highlights the potential
Laisen Cui, Haina Huang, Yubo Zheng, Jiahao Zhang, Han Hai, Kai Bian, Zhichao Feng, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shan Lu, Bojun Xie, Ke Gao, Benjie Wei, Ya Liu, Chunhui Sun, Hong Liu, Chao Liu   +16 more
wiley   +1 more source

Sodium tanshinone IIA sulfonate alleviates osteoarthritis through targeting SIRT1. [PDF]

Chin Med
Xu M, Sun X, Ma X, Qin Z, Gao X, Jin X, Sun H.   +6 more
europepmc   +1 more source

Evaluation of triply periodic minimal surface geometries in 3D‐printed PLA scaffolds for chondrogenic differentiation

Biotechnology Progress, EarlyView.
Abstract Triply periodic minimal surface (TPMS) scaffolds are gaining attention in tissue engineering due to their continuous and interconnected porous architecture. In this study, three TPMS geometries—Gyroid, Diamond, and I‐WP—were fabricated from polylactic acid (PLA) using fused deposition modeling (FDM), with all scaffolds designed to maintain the
Mahmut Alp Kılıç, Mustafa Akyürek, Roozbeh Abidnejad, Alp Karakoç   +3 more
wiley   +1 more source

Cuproptosis in osteoarthritis: Exploring chondrocyte cuproptosis and therapeutic avenues. [PDF]

J Orthop Translat
Hua H, Cheng F, Meng Z, Zhang A, Li M, Zhang M, Lou P, Zhu Y, Tong P, Zhang Y.   +9 more
europepmc   +1 more source