Results 181 to 190 of about 171,876 (350)

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

Triamcinolone Modulates Chondrocyte Biomechanics and Calcium-Dependent Mechanosensitivity. [PDF]

Int J Mol Sci
Liang C, Jud S, Frantz S, Riester R, Danalache M, Umrath F.   +5 more
europepmc   +1 more source

Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action. [PDF]

, 1986
Jane Chang, S C Gilman, Anthony Lewis
openalex   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

Biotechnology and Bioengineering, EarlyView.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen, Gabriella Faircloth, Nicole T. Marguerite, Mariachiara Conti, Ethan S. Lippmann, Jamey D. Young   +5 more
wiley   +1 more source

Near-infrared photobiomodulation stimulates viability and cartilage matrix synthesis in human chondrocytes. [PDF]

Sci Rep
Oliveira S, Ferreira D, Padrão J, Catarino SO, Monteiro F, Zille A, Rodrigues LR, Silva FS, Hinckel BB, Carvalho Ó, Leal A.   +10 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Erianin protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by activating GPX4/STING signaling in osteoarthritis. [PDF]

Inflamm Res
Li C, Jian W, Lu S, Wang Y, Fang C.
europepmc   +1 more source

SAT0062 Metabolomics and metabolic function analysis of the secretome of articular cartilage and chondrocytes in response to pro-inflammatory cytokines [PDF]

, 2018
Christopher R. Fellows, Helen Quasnichka, Namrata R. Chowdhury, Emma Budd, Debra J. Skene, Ali Mobasheri   +5 more
openalex   +1 more source

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

seneR: An R package for comprehensive senescence assessment and its application in type 2 diabetes and osteoarthritis. [PDF]

Comput Struct Biotechnol J
Zhang Y, Zhang X, Chen C, Li B, Lu Y, Ma X, Yang Y.   +6 more
europepmc   +1 more source