Results 211 to 220 of about 216,956 (381)

miR-708-5p Attenuates Osteoarthritis Progression via Multi-Target Modulation of the NOX4/NF-κB Axis and Cartilage Homeostasis. [PDF]

Cartilage
Huang SH, Liu ZM, Chen SJ, Tu PY, Tien YC, Lu CC, Wang CC, Chen LM, Shen PC.   +8 more
europepmc   +1 more source

Evaluation of potassium pyroantimonate/sucrose/glutaraldehyde concentration and incubation time as essential variables for localizing calcium bound to organic compounds in epiphyseal chondrocytes. [PDF]

, 1984
Herbert K. Kashiwa, N J Thiersch
openalex   +1 more source

A mouse coccygeal intervertebral disc degeneration model with tail‐looping constructed using a suturing method

Animal Models and Experimental Medicine, EarlyView.
A novel, simple coccygeal intervertebral disc degeneration model, using a suturing method for tail‐looping, without the need for external fixation and complex surgery. The model has high reproducibility and stability and overcomes the disadvantages of the existing animal models of disc degeneration.
Wei Xie, Zemao Huang, Ziyang Huang, Deqing Luo, Zhangxin Chen, Li Xie, Lingqi Zhu, Hui Liu, Kejian Lian, Paolo Alberton, Denitsa Docheva, Dasheng Lin   +11 more
wiley   +1 more source

Y-box binding protein 1 stabilizes EP300 mRNA and promotes forkhead box C1 H3K27Ac to aggravate chondrocyte injury in osteoarthritis. [PDF]

J Cell Commun Signal
Li J, Zhou G, Chen T, Lin Q, Yang Q.
europepmc   +1 more source

Controlling chondrocyte senescence [PDF]

Nature Reviews Rheumatology, 2019
openaire   +2 more sources

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

PTHrP buffers Wnt/β-catenin activity through a PKC-ζ involved negative feedback loop to maintain articular cartilage homeostasis and attenuate osteoarthritis. [PDF]

J Orthop Translat
Tong WX, Chen HJ, Huang ZL, Zhao D, Hu J.   +4 more
europepmc   +1 more source

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

Animal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu, Qi Liu, Shuyan Xue, Siyuan Li, Nan Nan, Yang Liu, Huiqin Hao   +6 more
wiley   +1 more source

Genetically engineered chondrocyte-mimetic nanoplatform attenuates osteoarthritis by blocking IL-1β and restoring sirtuin-3. [PDF]

Sci Adv
Deng C, Yu L, Zhao X, Chen Y, Mei J, Wei J, Chen X, Lei G, Zeng C.   +8 more
europepmc   +1 more source

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

Proceedings of the National Academy of Sciences of the United States of America, 2014
Liu Yang, K. Tsang, Hoi-ching Tang, D. Chan, K. Cheah   +4 more
semanticscholar   +1 more source