The role of cytokines in ovarian cancer drug resistance
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang+7 more
wiley +1 more source
Conjoint analysis of single-cell sequencing and high-throughput virtual screening regarding DDR2 in osteoarthritis disease models. [PDF]
Mei H+7 more
europepmc +1 more source
Observations on the structural features of the chondrocytes in the hypertrophic zone.
Shunichi Shibata
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What's New? Estrogen receptors likely influence the development of laryngeal cancer and are of particular interest in regard to their relationship with the vitamin D metabolite 24R,25(OH)2D3. In this study the authors examined interactions between 24R,25(OH)2D3 and estrogen‐responsive laryngeal tumorigenesis.
Cydney D. Dennis+10 more
wiley +1 more source
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation. [PDF]
Zai Z+10 more
europepmc +1 more source
Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via the NF‐κB/NLRP3 pathway and downregulates CD68 expression in smooth muscle cells (SMCs), contributing to reduced vascular inflammation.
Baiyi Lu+10 more
wiley +1 more source
The Senotherapeutic Effects of APPA (Apocynin [AP] and Paeonol [PA]) on Senescent Human Chondrocytes. [PDF]
Fernández-Moreno M+6 more
europepmc +1 more source
Akermanite scaffolds promote osteogenic differentiation of BMSCs through regulating the PI3K/Akt signaling pathway, and strontium ions enhance the akermanite effects by mediating the cytokine‐cytokine receptor interaction pathway. Thus, the enhancements of osteogenesis in subchondral bone coupled with the chondral‐promoting effects of chondrocytes ...
Bo Li+15 more
wiley +1 more source
Expression Analysis of Mesenchymal Stem/Progenitor Cell Markers on Chondrocytes in Ossification of the Posterior Longitudinal Ligament. [PDF]
Tsuji T+6 more
europepmc +1 more source