Results 251 to 260 of about 171,876 (350)

Increased TNN in Knee Osteoarthritis Accelerates Cartilage Damage via the Negative Regulation of AMPK-PPARγ Signalling. [PDF]

J Cell Mol Med
Chen Z, Wu G, Fan Y, Li C, Wang C, Yang C, Wu S, Wu Z, Wang P, Zhang Y, You W.   +10 more
europepmc   +1 more source

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Hypoxia-preconditioned bone marrow mesenchymal stem cell-derived exosomes ameliorate knee osteoarthritis by promoting cartilage regeneration and alleviating pain in rats. [PDF]

Regen Ther
Zhang B, Lu C, Dou B, Gu W, Li K.
europepmc   +1 more source

T‐Cell Signaling Pathways, Including Exhaustion, Predominate in Unhealthy Visceral and Subcutaneous Adipose Tissues

Obesity, EarlyView.
ABSTRACT Objective Obesity is an imperfect correlate of metabolic health. Visceral adipose tissue (VAT) characteristics are considered determinants of poor health and subcutaneous adipose tissue (SAT) considered protective. There is a gap in knowledge regarding shared vs.
Sobha Puppala, Alyssa R. Hamann, Christina M. Stevens, Alistaire Ruggiero, Laura A. Cox, Kylie Kavanagh   +5 more
wiley   +1 more source

Mitochondria relay cholesterol signal exacerbates osteoarthritis in mice. [PDF]

Nat Commun
Ma Y, Pang Y, Liu C, Tian Y, Zheng K, Yao M, Liu X, Cao R, Zhao Y, Zheng Z, Jia W, Zhu D, Peng H, Du D, Qu X, Liu CJ, Yang P, Huang Y, Zhang C, Gao J.   +19 more
europepmc   +1 more source

P127 TGFb3 MODULATES NOTCH-1 PROTEIN EXPRESSION LEVELS IN HUMAN ARTICULAR CHONDROCYTES AND MESENCHYMAL STEM CELLS

, 2006
Shawn P. Grogan, T Olee, Kristen Johnson, Robert Terkeltaub, Martin Lotz   +4 more
openalex   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source

Joint Acidosis and GPR68 Signaling in Osteoarthritis: Implications for Cartilage Gene Regulation. [PDF]

Genes (Basel)
Hyde C, Yung A, Taffe R, Patel B, Khan NM.   +4 more
europepmc   +1 more source

Scaffold-dependent differentiation of human articular chondrocytes

, 1998
Schlegel
openalex   +2 more sources

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source