Results 261 to 270 of about 171,876 (350)

A vast stem-progenitor cell pool, richly vascular system, and hybrid ossification drive the daily centimeter-scale elongation of bony antlers. [PDF]

Imeta
Ba H, He S, Sun HX, Wang X, Zhang H, Deng Q, Yuan Y, Liu C, Wang Z, Li J, Xie L, Tang Y, Wang J, Ma C, Li N, Hu P, Guo Q, Zhang G, Coates DE, Gu Y, Liu C, Wang D, Li C.   +22 more
europepmc   +1 more source

Effect of lncRNA Zeb1-As1 on Il-1B-Induced Chondrocyte Injury by Regulating Mir-330-3p Expression

, 2020
Wei Dai, Yuchen Zhu, Siqi Song, Ling Chai, Xin Mu   +4 more
openalex   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Construction of biomimetic gradient-structured cartilage organoids and mechanistic study of their application for cartilage rejuvenation. [PDF]

Bioact Mater
Miao X, Kong K, Rong K, Song Q, Guo T, Zhang C, Wu Q, Zhai Z, Sun Y, Gan Y, Xiang M, Dai K, Atala A, Lu Z.   +13 more
europepmc   +1 more source

Injectable Biomimetic Composite Hydrogel Scaffold With Tissue‐Engineered Cartilage Matrix for Articular Cartilage Regeneration

Rare Metals, EarlyView.
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu, Jun‐Jie Jiang, Hang Yao, Xian‐Feng Shang, Ming‐Di Zheng, Xu Hu, Shuo Xu, Jun‐Li Shi, Yan Han, Chi‐Run Wang, Qi Tao, Huai‐Guo Xue, Dong‐An Wang, Yu‐Chi Zhao   +13 more
wiley   +1 more source

miR-1737 targets TAK1 to mediate the BMP-Smad signaling pathway to regulate the molecular mechanism of chicken tibial chondrodysplasia. [PDF]

Poult Sci
Xu H, Du R, Xie X, Lu Y, Hu Z, Ji X, Guo L, Wang X, Liu Y, Zhang Z, Wang Y.   +10 more
europepmc   +1 more source

Extracellular Vesicles Released From Articular Chondrocytes Play a Major Role in Cell–Cell Communication

, 2019
Xiaoming Liu, Claire Shortt, Fenglin Zhang, Mariah Q. Bater, Mary K. Cowman, Thorsten Kirsch   +5 more
openalex   +2 more sources

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

Rare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu, Shao‐Sheng Jia, Rong‐Bang Sun, Tong Zhang, Ling‐Chuang Bai, Di Mei, Shi‐Jie Zhu, Lan Chen, Shao‐Kang Guan   +8 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Heat shock proteins in osteoarthritis: molecular mechanisms, pathogenic roles, and therapeutic opportunities. [PDF]

Front Immunol
Zhao B, Deng Z, Yang Z, Yang F, Yang W.
europepmc   +1 more source