Results 261 to 270 of about 222,465 (345)

Activation of β‐Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis‐Like Phenotype in Adult β‐Catenin Conditional Activation Mice

Journal of Bone and Mineral Research, 2009
Mei Zhu, Dezhi Tang, Qiuqian Wu, Suyang Hao, Mo Chen, Chao Xie, R. Rosier, Regis J. O'Keefe, M. Zuscik, Di Chen   +9 more
semanticscholar   +1 more source

Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator. Bone mineral density (BMD), bone volume/total volume
Qing Su, Jia Chen
wiley   +1 more source

Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model. [PDF]

Front Bioeng Biotechnol
Huang Z, Zhao W, Lan J, Lin Y, Gao X.
europepmc   +1 more source

PA67 The effects of cannabinoids on chondrocyte nitric oxide production and cartilage proteoglycan breakdown

, 2001

openalex   +1 more source

Enhancing Chondrogenic Phenotype for Cartilage Tissue Engineering: Monoculture and Coculture of Articular Chondrocytes and Mesenchymal Stem Cells

Tissue engineering. Part B, Reviews, 2014
K. Hubka, R. Dahlin, V. Meretoja, F. Kasper, A. Mikos   +4 more
semanticscholar   +1 more source

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Integration of Network Pharmacology, Molecular Docking, and Experimental Validation to Identify the Effect of EGCG on Alleviating Chondrocyte Inflammatory Damage by Targeting ER Stress-STAT3 Crosstalk. [PDF]

J Inflamm Res
Zhao MJ, Yin JL, Luo JH, Ge YS, Huang CM, Meng TT, Wang XZ, Huang XH, Chen LL, Zhai YQ, Wu XB, Ding DF.   +11 more
europepmc   +1 more source

Post‐operative joint stiffness after Bereiter trochleoplasty does not affect 2‐year improvement in patient‐reported outcomes. A prospective cohort study of 374 Bereiter trochleoplasties

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Bereiter trochleoplasty (TP) is a well‐described procedure to address trochlear dysplasia (TD). Post‐operative joint stiffness with reduced range of motion (ROM) is a common complication usually requiring arthroscopically assisted manipulation (AAM) with the removal of adhesions and scar tissue. Inferior clinical outcomes after TP have
Christian Dippmann, Christos Soleas, Anke Simone Rechter, Volkert Siersma, Kristoffer Weisskirchner Barfod, Peter Lavard   +5 more
wiley   +1 more source

A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis. [PDF]

J Nanobiotechnology
Huang H, Tang M, Hu P, Zhan Y, Sun W, Zheng W, Zhu J, Chen J, Xue S, Huang S, Han W, Zhang C, Ding C, Zhang Y, Li S, Ruan G.   +15 more
europepmc   +1 more source

Insulin-Transferrin-Selenium Prevent Human Chondrocyte Dedifferentiation And Promote The Formation Of High Quality Tissue Engineered Human Hyaline Cartilage

, 2005
Chua Kh, BS Aminuddin, N H Fuzina, BHI Ruszymah   +3 more
openalex   +1 more source