Results 271 to 280 of about 97,024 (315)
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Arthroscopy: The Journal of Arthroscopic & Related Surgery, 1996
The transplantation of chondrocytes as a treatment to repair defects and degeneration in hyaline articular cartilage is being tested in numerous laboratory and clinical settings. This has included transplanting chondrocytes grown in tissue culture that were procured from non-weight-bearing areas of the affected joint to transplanting allografts with ...
D W, Jackson, T M, Simon
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The transplantation of chondrocytes as a treatment to repair defects and degeneration in hyaline articular cartilage is being tested in numerous laboratory and clinical settings. This has included transplanting chondrocytes grown in tissue culture that were procured from non-weight-bearing areas of the affected joint to transplanting allografts with ...
D W, Jackson, T M, Simon
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Autologous Chondrocyte Implantation
The Journal of Bone & Joint Surgery, 2006Injuries to joint surfaces can result from acute high-impact or repetitive shear and torsional loads to the superficial zone of the articular cartilage architecture. The use of autologous chondrocyte implantation is promising and is associated with several potential long-term benefits.
Jones, D. G., Peterson, L.
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Science Translational Medicine, 2018
An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
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An innovative strategy for delivering drugs to chondrocytes in situ offers new avenues for treating osteoarthritis (Geiger et al ., this issue).
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1995
Data obtained while investigating growth plate chondrocyte differentiation during endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis depends on positional signaling mediated by selected homeobox-containing genes and soluble mediators.
R, Cancedda +2 more
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Data obtained while investigating growth plate chondrocyte differentiation during endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis depends on positional signaling mediated by selected homeobox-containing genes and soluble mediators.
R, Cancedda +2 more
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A biography of the chondrocyte
Annals of the Rheumatic Diseases, 2008Significant gaps persist in our understanding of chondrocyte biology. We do not know when, how, or even whether these cells are replenished throughout the normal, human life span. We are taught that as much as 90% of the cartilage is "metabolically inert" interterritorial matrix, but we do not know how this substance is regularly replaced (as it is ...
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Prevention of Chondrocyte Apoptosis
The Journal of Bone and Joint Surgery-American Volume, 2001The occurrence of chondrocyte apoptosis may be critical in determining the extent of a lesion and subsequent repair after mechanical injury to articular cartilage. Agents that prevent apoptosis and increase chondrocyte survival may prove beneficial in the treatment of these lesions.
Darryl D. D'Lima +4 more
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In situ chondrocyte viscoelasticity
Journal of Biomechanics, 2012It has been proposed, based on theoretical considerations, that the strain rate-dependent viscoelastic response of cartilage reduces local tissue and cell deformations during cyclic compressions. However, experimental studies have not addressed the in situ viscoelastic response of chondrocytes under static and dynamic loading conditions. In particular,
Ziad Abusara +3 more
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Tissue Engineering with Chondrocytes
Facial Plastic Surgery, 2002Tissue engineering of cartilage, using chondrocytes based on the use of synthetic biodegradable polymer cell delivery vehicles (scaffolds), is an alternate treatment modality for replacing missing cartilage. Cartilage tissue engineering has an important role to play in the generation of graft material for head and neck reconstruction. It is an approach
R. James Koch, Goutham Krishna Gorti
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Phenotype of chondrocytes in osteoarthritis
Biorheology, 2008Articular cartilage is composed by a unique cell population, the chondrocytes, embedded in an abundant extra-cellular matrix (ECM). Growth, differentiation and homeostasis of the cartilage are regulated by an intricate interplay between the chondrocytes and ECM, which allows the matrix to send signals to the chondrocytes and the chondrocytes to sense ...
IANNONE, Florenzo, LAPADULA, Giovanni
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Mitochondrial granules in chondrocytes
Calcified Tissue Research, 1969Rat and mice epiphyseal growth plates were studied with the electron microscope. A gradient of mitochondrial electron-dense granules was found. Chondrocytes in the proliferative zone had few granules, while those of the succeeding zones showed a gradual increase in number and density until the zone of provisional calcification was reached.
J. H. Martin, J. L. Matthews
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