Step‐Ladder Bioprinting to Align Collagen Fibers for Anisotropic Tissue Fabrication
The step‐ladder printing platform includes successive segments of channels with varying widths in a custom barrel design. This design allows for improved anisotropy of collagen fibers during extrusion. To demonstrate its effectiveness, corneal constructs with high transparency and shape fidelity, as well as articular cartilage constructs, displaying ...
Ilayda Namli +8 more
wiley +1 more source
Chondrocyte-Targeted Nanoparticles Loaded with <i>N</i>-Acetylcysteine Protect Articular Cartilage and Attenuate Osteoarthritis by Inhibiting Ferroptosis via Glutathione Maintenance. [PDF]
Wang S +8 more
europepmc +1 more source
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang +9 more
wiley +1 more source
Single-cell analysis of the somatic mutational landscape in human chondrocytes during aging and in osteoarthritis. [PDF]
Ren P +16 more
europepmc +1 more source
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes. [PDF]
Yanagihara Y +6 more
europepmc +1 more source
PIEZO1 is highly correlated with mechanical stimulation, controlling bone growth and remodeling, while showing specific distribution characteristics under distinct loads. Upon dialectical review, this manuscript proposes that PIEZO1 could serve as a target for osteoporosis and a quantitative indicator for monitoring bone health in real‐time.
Chunyu Zhang, Yuehong Wang
wiley +1 more source
Bimetallic Copper-Manganese Zeolitic Imidazolate Framework Nanozyme Scavenges Reactive Oxygen Species to Alleviate Osteoarthritis via Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Axis and Autophagic Flux Restoration. [PDF]
Zheng X +9 more
europepmc +1 more source
A Clinical Study of the Distribution and Morphology of Harris Lines
ABSTRACT Harris lines are commonly used in bioarcheology to infer lifestyle in ancient populations; however, their etiology and identification parameters are still under debate. The aim of this study is to observe the distribution of the lesions in a contemporary clinical sample to address their association with etiological factors, age, biological sex,
Claudia Moro +7 more
wiley +1 more source

