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Not all chondroitin sulfates are the same
Not all chondroitin sulfates are the ...
VOLPI, Nicola
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CHONDROITIN, A NEW MUCOPOLYSACCHARIDE
E A, DAVIDSON, K, MEYER
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Chondroitin Product Selection for the Glucosamine/Chondroitin Arthritis Intervention Trial
Journal of the American Pharmacists Association: JAPhA, 2006To select a high-quality chondroitin dosage form and/or an appropriate source of sodium chondroitin for the National Institutes of Health's Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT).Controlled experimental trials.Laboratory.Not applicable.Commercially available chondroitin products were reviewed, and purified sodium chondroitin from ...
Daniel O Clegg +2 more
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Matrix Biology, 1993
Monoclonal antibodies have been developed that recognize epitopes in native chondroitin sulfate chains. One of these antibodies, CS-56, reportedly recognizes chondroitin 4- and 6-sulfates. However, this antibody, and four other anti-chondroitin sulfate antibodies, 4C3, 4D3, 6C3 and 7D4, do not recognize epitopes in chondroitin sulfate chains from Swarm
Arnold Caplan +2 more
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Monoclonal antibodies have been developed that recognize epitopes in native chondroitin sulfate chains. One of these antibodies, CS-56, reportedly recognizes chondroitin 4- and 6-sulfates. However, this antibody, and four other anti-chondroitin sulfate antibodies, 4C3, 4D3, 6C3 and 7D4, do not recognize epitopes in chondroitin sulfate chains from Swarm
Arnold Caplan +2 more
exaly +3 more sources
Chondroitin sulfates (CS) account for more than 80% of glycosaminoglycans of articular cartilage, which imparts its physiological functions. We quantified the absolute concentration of the CS components of the full thickness cartilages from the knees of ...
Pi-Hui Liang +2 more
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Production of chondroitin sulfate and chondroitin
Applied Microbiology and Biotechnology, 2010The production of microbial polysaccharides has recently gained much interest because of their potential biotechnological applications. Several pathogenic bacteria are known to produce capsular polysaccharides, which provide a protection barrier towards harsh environmental conditions, and towards host defences in case of invasive infections.
SCHIRALDI, Chiara +2 more
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Chondroitin as metabolic precursor of chondroitin sulfate in bovine cornea
Experimental Eye Research, 1972Abstract The low sulfated chondroitin sulfate fraction isolated and purified from bovine cornea was shown to consist of numerous molecular species ranging in their sulfate-hexosamine ratio from 0·2 – 0·9. On incubation of cornea in vitro, under appropriate conditions in the presence of 35S-sulfate, all chondroitin sulfates were obtained in the 35S ...
H, Bleckamnn, E, Buddecke
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Microbial production and metabolic engineering of chondroitin and chondroitin sulfate
Emerging Topics in Life Sciences, 2018Several commercial uses and potential novel applications have recently been described for chondroitin sulfate (CS). However, the currently applied animal extractive procedure has a high environmental impact, which may become more profound especially in relation to the forecasted expansion of the CS market for applications as a food supplement ...
Cimini D., Restaino O. F., Schiraldi C.
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Macromolecular assembly of chondroitin
Biochemical and Biophysical Research Communications, 1972Abstract A microsomal preparation from chick embryo epiphyseal cartilage has been used to study the assembly of the heteropolysaccharide, chondroitin. Endogenous chondroitin sulfate in the microsomal preparation was found to act as a primer for the addition of relatively short non-sulfated polysaccharide chains to form large molecules with a large ...
M E, Richmond, S, DeLuca, J E, Silbert
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Glucosamine and Chondroitin Sulfate
Rheumatic Disease Clinics of North America, 2011Glucosamine and chondroitin sulfate, components of normal cartilage that are marketed as dietary supplements in the United States, have been evaluated for their potential role in the treatment of osteoarthritis. Due to claims of efficacy, increased prevalence of osteoarthritis, and a lack of other effective therapies, there has been substantial ...
Karla L, Miller, Daniel O, Clegg
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