Results 91 to 100 of about 21,815 (286)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Reprogramming Metabolic Flux in Escherichia Coli to Enhance Chondroitin Production
Advanced ScienceReprogramming metabolic flux is a promising approach for constructing efficient microbial cell factories (MCFs) to produce chemicals. However, how to boost the transmission efficiency of metabolic flux is still challenging in complex metabolic pathways ...
Chunlei Zhao +8 more
doaj +1 more source
, 2012 Juqun Xi,1 Jin Qin,2 Lei Fan21Department of Pharmacology, Yangzhou University Medical Academy, Yangzhou, People's Republic of China; 2School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, People's Republic of ...
Xi J, Qin J, Fan L
core
Splenic Delivery System of pDNA through Complexes Electrostatically Constructed with Protamine and Chondroitin Sulfate [PDF]
, 2018 We developed and optimized a novel gene delivery vector constructed electrostatically with an anionic biological component and a cationic biological component.
Hitoshi Sasaki +19 more
core +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Oxygen supply is a critical parameter in 3D cell cultivation using bioreactors. Since bioreactor designs often prioritise practical constraints, understanding the oxygen supply dynamics of the media is crucial for achieving either uniform or spatially controlled oxygen delivery.
Franziska Alt +4 more
wiley +1 more source
A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern
, 2003 The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Christodoulou, Z +14 more
core +1 more source
Glucosamine and Chondroitin for Osteoarthritis
Journal of International Medical Research, 2008 Osteoarthritis (OA) is a common, chronic disease that most frequently affects the knees and is a major cause of disability in the elderly. It is characterized by progressive cartilage loss, accompanied by secondary changes such as osteophyte formation and calcium deposition.
openaire +2 more sources
New opportunities for bioscaffold‐enabled spinal cord injury repair
BMEMat, EarlyView.Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi +11 more
wiley +1 more source
Effects of chondroitin sulfate B on the reconstitution of collagen fibrils
Nihon Kikai Gakkai ronbunshu, 2017 Collagen fibrils were reconstituted in vitro from type I collagen solution. The reconstituted collagen fibrils and chondroitin sulfate B were deposited alternately.
Noritaka YAMAMOTO, Ken SASAKI
doaj +1 more source
Causal Effect of Chondroitin, Glucosamine, Vitamin, and Mineral Intake on Kidney Function: A Mendelian Randomization Study [PDF]
, 2023 Jeong-Min Cho +15 more
openalex +1 more source