Results 91 to 100 of about 54,528 (266)

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

Chondroitin sulfate. Structure, role and pharmacological activity. Nicola Volpi (Editor) [PDF]

open access: yes, 2006
Contents STRUCTURE Isolation, purification and analysis of chondroitin sulfate proteoglycans Fumiko Matsui and Atsuhiko Oohira Isolation and Purification of Chondroitin Sulfate Luiz-Claudio F. Silva Structure of chondroitin sulfate Fotini N. Lamari and
VOLPI, Nicola
core  

Expanding the chondroitin glycoproteome of Caenorhabditis elegans [PDF]

open access: yes, 2018
Chondroitin sulfate proteoglycans (CSPGs) are important structural components of connective tissues in essentially all metazoan organisms. In vertebrates, CSPGs are involved also in more specialized processes such as neurogenesis and growth factor ...
Noborn, Fredrik,   +20 more
core   +1 more source

Technology and Properties of Chondroitin Sulfate from Marine Hydrobionts [PDF]

open access: yes, 2020
Chondroitin sulfate was isolated from the cartilage tissue of salmon (Salmo salar), northern skate (Raja hyperborean) and black-shark (Galeus melastomus). The polysaccharide content is from 67.1% to 82.2% in the samples.
Konovalova, Irina   +7 more
core   +2 more sources

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Chondroitin sulfates modulate axon guidance in embryonic Xenopus brain [PDF]

open access: yes, 1998
Chondroitin sulfate proteoglycans display both inhibitory and stimulatory effects on cell adhesion and neurite outgrowth in vitro. The functional activity of these proteoglycans appears to be context specific and dependent on the presence of different ...
Walz, A.   +7 more
core   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu   +23 more
wiley   +1 more source

Classification of chondroitin sulfate A, chondroitin sulfate C, glucosamine hydrochloride and glucosamine 6 sulfate using chemometric techniques. [PDF]

open access: yes, 2005
Chondroitin sulfate A, chondroitin sulfate C, glucosamine hydrochloride and glucosamine sulfate are natural products that are becoming increasingly popular in the treatment of arthritis.
Foot, M, Mulholland, M
core   +1 more source

Reprogramming Metabolic Flux in Escherichia Coli to Enhance Chondroitin Production

open access: yesAdvanced Science
Reprogramming metabolic flux is a promising approach for constructing efficient microbial cell factories (MCFs) to produce chemicals. However, how to boost the transmission efficiency of metabolic flux is still challenging in complex metabolic pathways ...
Chunlei Zhao   +8 more
doaj   +1 more source

Glucosamine and Chondroitin for Osteoarthritis

open access: yesJournal of International Medical Research, 2008
Osteoarthritis (OA) is a common, chronic disease that most frequently affects the knees and is a major cause of disability in the elderly. It is characterized by progressive cartilage loss, accompanied by secondary changes such as osteophyte formation and calcium deposition.
openaire   +2 more sources

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