Results 111 to 120 of about 16,160 (157)
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The biosynthesis of chondroitin sulfate
Archives of Biochemistry and Biophysics, 1966Abstract A particulate enzyme preparation from embryonic chick cartilage catalyzes incorporation of radioactivity from UDP-GalNAc- 3 H or UDP-Glc-UA- 14 C into chondroitin sulfate. In the absence of added oligosaccharide acceptor, incorporation of radioactivity from either nucleotide required the presence of the alternate unlabeled nucleotide ...
A, Telser, H C, Robinson, A, Dorfman
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Structure of Chondroitin Sulfate
2006Publisher Summary This chapter presents the up‐to‐date information on the structure of chondroitin sulfate (CS) and dermatan sulfate (DS). CS is an anionic linear polysaccharide, which is synthesized as part of proteoglycan (PG) molecules in vertebrates and invertebrates.
Fotini N, Lamari, Nikos K, Karamanos
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The Journal of Biochemistry, 1979
By heating the pyridinium salts of chondroitin 4- and 6-sulfates in dimethyl sulfoxide containing 10% of water or methanol at 80 degrees C for 1--5 h, several chondroitin preparations with sulfur contents of 0.02--1.05% were prepared in 83--96% yields, respectively.
K, Nagasawa, Y, Inoue, T, Tokuyasu
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By heating the pyridinium salts of chondroitin 4- and 6-sulfates in dimethyl sulfoxide containing 10% of water or methanol at 80 degrees C for 1--5 h, several chondroitin preparations with sulfur contents of 0.02--1.05% were prepared in 83--96% yields, respectively.
K, Nagasawa, Y, Inoue, T, Tokuyasu
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Journal of Molecular Structure: THEOCHEM, 2004
Abstract Molecular modeling of glycosaminoglycans, hyaluronan, chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate and keratan sulfate is presented. Semiempirical quantum mechanical calculations, PM3 method, have been used to locate the minimal energy regions in the conformational space around the β 1→3 and β 1→4 glycosidic linkages. The global
Halil Bayraktar +3 more
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Abstract Molecular modeling of glycosaminoglycans, hyaluronan, chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate and keratan sulfate is presented. Semiempirical quantum mechanical calculations, PM3 method, have been used to locate the minimal energy regions in the conformational space around the β 1→3 and β 1→4 glycosidic linkages. The global
Halil Bayraktar +3 more
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Biosynthesis of Chondroitin Sulphates
Nature, 1959LITTLE information is available regarding the biosynthesis of acid mucopolysaccharides. Knowledge of biosynthetic pathways to the chondroitin sulphates in particular is practically confined to the fact that glucose is utilized for both the hexosamine and uronic acid moieties1 and that 3′—phosphoadenosine 5′—phosphosulphate (PAPS) is involved in ...
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Sequential synthesis of chondroitin oligosaccharides by immobilized chondroitin polymerase mutants
Glycoconjugate Journal, 2008Escherichia coli strain K4 expresses a chondroitin (CH)-polymerizing enzyme (K4CP) that contains two glycosyltransferase active domains. K4CP alternately transfers glucuronic acid (GlcA) and N-acetyl-galactosamine (GalNAc) residues using UDP-GlcA and UDP-GalNAc donors to the nonreducing end of a CH chain acceptor.
Nobuo, Sugiura +5 more
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The Journal of Organic Chemistry, 2019
Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays essential roles in physiological processes. Here we report a facile approach to a library of CS tetra- and hexasaccharides based on the enzymatic degradation of chondroitin over 10 or 11 steps, which is the shortest synthetic route toward size-defined CS ...
Xiao Zhang +4 more
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Chondroitin sulfate (CS) is a structurally complex polyanionic glycosaminoglycan that plays essential roles in physiological processes. Here we report a facile approach to a library of CS tetra- and hexasaccharides based on the enzymatic degradation of chondroitin over 10 or 11 steps, which is the shortest synthetic route toward size-defined CS ...
Xiao Zhang +4 more
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Isomeric Chondroitin Sulphates
Nature, 1958A RECENT communication1 claims to “confirm Meyer's hypothesis that chondroitin sulphates A and C are only two fractions of the same polydisperse substance”. Apparent lack of agreement in nomenclature2–4 further emphasizes the need for clear differentiation of the isomeric chondroitin sulphates of connective tissue.
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Journal of Consumer Health On the Internet, 2006
Results of the four-year study entitled the Glucosamine/ chondroitin Arthritis Intervention Trial (GAIT) provided partial answers to those seeking relief from arthritis pain. Scientists will continue studying the efficacy of these substances as pain remedy and cartilage rejuvenator.
Suzanne M. Shultz, Esther Y. Dell
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Results of the four-year study entitled the Glucosamine/ chondroitin Arthritis Intervention Trial (GAIT) provided partial answers to those seeking relief from arthritis pain. Scientists will continue studying the efficacy of these substances as pain remedy and cartilage rejuvenator.
Suzanne M. Shultz, Esther Y. Dell
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Biosynthesis of chondroitin sulfate. Assembly of chondroitin on microsomal primers
Biochemistry, 1973M E, Richmond, S, DeLuca, J E, Silbert
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