Results 161 to 170 of about 21,815 (286)
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
A novel chondroitin sulfate hydrogel for nerve repair
, 2011 Brachial plexus injuries affect numerous patients every year, with very debilitating results. The majority of these cases are very severe, and involve damage to the nerve roots.
Conovaloff, Aaron William
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Phosphorylation of chondroitin sulfate in proteoglycans from the swarm rat chondrosarcoma.
, 1984 Theodore R. Oegema +3 more
openalex +1 more source
Tendon stem cells seeded on dynamic chondroitin sulfate and chitosan hydrogel scaffold with BMP2 enhance tendon-to-bone healing [PDF]
, 2023 Qingsong Zhang +3 more
openalex +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
The FEBS Journal, EarlyView.Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal +5 more
wiley +1 more source
Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor +9 more
wiley +1 more source
Glucosamine and Chondroitin for Osteoarthritis
, 2006 Clinical Question: Does glucosamine or chondroitin reduce pain, improve functional status, or improve prognosis in patients with ...
Fox, Beth Anne +2 more
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