Glucosamine and chondroitin for osteoarthritis [PDF]
H, Akama, S, Saito
openaire +2 more sources
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki +4 more
wiley +1 more source
Holothurian Fucosylated Chondroitin Sulfate
Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
Vitor Pomin, Vitor H. Pomin
core +1 more source
Structure of the Chondroitin 4-Sulfate-Protein Linkage Region
Lennart Rodén, Gérard Armand
openalex +1 more source
Chondroitin Sulfate-Modified Liposomes for Targeted Co-Delivery of Doxorubicin and Retinoic Acid to Suppress Breast Cancer Lung Metastasis [PDF]
Zhiwei Zhang, Lixin Ma, Jingwen Luo
openalex +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Anti-inflammatory activity of chondroitin sulfate
Chondroitin sulfate is a biomolecule which has increasingly focused the interest of many research groups due to its possible anti-inflammatory activity.
VOLPI, Nicola
core
Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI [PDF]
Lukas Wildi +8 more
openalex +1 more source
Risk of ischaemic stroke among new users of glucosamine and chondroitin sulphate: a nested case–control study [PDF]
Ramón Mazzucchelli +13 more
openalex +1 more source

