Results 151 to 160 of about 21,815 (286)

Glucosamine and chondroitin for osteoarthritis [PDF]

open access: yesArthritis & Rheumatism, 2001
H, Akama, S, Saito
openaire   +2 more sources

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

open access: yesThe FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki   +4 more
wiley   +1 more source

Holothurian Fucosylated Chondroitin Sulfate

open access: yes, 2014
Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
Vitor Pomin, Vitor H. Pomin
core   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Anti-inflammatory activity of chondroitin sulfate

open access: yes, 2007
Chondroitin sulfate is a biomolecule which has increasingly focused the interest of many research groups due to its possible anti-inflammatory activity.
VOLPI, Nicola
core  

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI [PDF]

open access: bronze, 2011
Lukas Wildi   +8 more
openalex   +1 more source

Risk of ischaemic stroke among new users of glucosamine and chondroitin sulphate: a nested case–control study [PDF]

open access: gold, 2022
Ramón Mazzucchelli   +13 more
openalex   +1 more source

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