Results 291 to 300 of about 93,694 (356)

Omics‐derived biological modules reflect tau positron emission tomography in Alzheimer's disease

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 4, October-December 2025.
Abstract BACKGROUND Tau neurofibrillary pathology is a hallmark of Alzheimer's disease (AD) and can be quantified in vivo using tau‐selective positron emission tomography (tau PET). Tau PET signal closely correlates with cognitive decline and disease stage, yet the molecular networks underpinning tau accumulation remain incompletely defined. METHODS We
Si‐Chun Gu   +6 more
wiley   +1 more source

Investigating the Effects of Epac2 Activation in an In Vitro Cortical Mechanical Injury Model for Central Nervous System Repair

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Study design. An in vitro cortical mechanical injury model for central nervous system repair, which contained five major neural tissue cells, is established from rats. After 7 days in vitro, the injuries are introduced, and Epac2 agonist S‐220 treatments are applied immediately after injury.
Hongming Ma   +2 more
wiley   +1 more source

Expression of Heart Development Protein With EGF‐Like Domains 1 (HEG1) Decorated With Low‐Sulfated Keratan Sulfate in Human Malignant Pleural Mesothelioma

open access: yesPathology International, Volume 75, Issue 10, Page 504-512, October 2025.
The purpose of this study is to investigate sulfation modification of the glycan structure decorating HEG1, one of the diagnostic markers of malignant pleural mesothelioma (MPM), in MPM. Immunohistochemical analysis reveals low‐sulfated keratan sulfate (KS) expression, recognized by 294‐1B1 and R‐10G, in MPM tissues with HEG1 expression.
Koki Nakashima   +9 more
wiley   +1 more source

Diagnostic accuracy of dual energy computed tomography for suspected pyogenic spondylodiscitis. [PDF]

open access: yesSci Rep
Stelbrink C   +9 more
europepmc   +1 more source

Using phenotyping to visualize and identify selfish bacteria: a methods guide. [PDF]

open access: yesMicrobiol Spectr
Reintjes G   +4 more
europepmc   +1 more source

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