Results 131 to 140 of about 435,081 (300)

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

open access: yesCell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai   +22 more
wiley   +1 more source

Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo   +3 more
wiley   +1 more source

Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy

open access: yesScience Translational Medicine, 2018
S. Pellegatta   +11 more
semanticscholar   +1 more source

Equine temporomandibular joint diseases: A systematic review

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The temporomandibular joint (TMJ) is a unique joint that enables mandibular movement. Temporomandibular diseases (TMDs) impair joint function, leading to more or less specific clinical signs. Objectives To compile and disseminate clinical data and research findings from existing publications on equine TMD.
Tomasz Jasiński   +5 more
wiley   +1 more source

The O-Serine Linkage in Peptides of Chondroitin 4- or 6-Sulfate

open access: hybrid, 1965
Bonnie Anderson   +2 more
openalex   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro

open access: yesThe FEBS Journal, EarlyView.
Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan   +8 more
wiley   +1 more source

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