Results 151 to 160 of about 77,038 (354)

Dual Growth Factor Release From Collagen Based Multilayer Films on Ti‐Surfaces Enhances Periimplant Bone Formation and Angiogenic Activity—An Experimental In‐Vivo Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The aim of the present study was to assess the effect of dual growth factor release from collagen‐based polyelectrolyte multilayer films (PEMs) on titanium implants on periimplant bone formation and angiogenetic activity in minipig mandibles.
Philipp Kauffmann   +7 more
wiley   +1 more source

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

open access: yesCell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai   +22 more
wiley   +1 more source

Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims In the therapy of type 1 diabetes mellitus, the subcutaneous space has been suggested to be a clinically preferable transplantation site for pancreatic islets due to its easy accessibility. However, its poor vascularisation capacity and, thus, challenging environment typically result in islet engraftment failure.
Selina Wrublewsky   +11 more
wiley   +1 more source

Chondroitin sulfate: An ideal biomaterial based scaffolds for cartilage regeneration and its therapeutic potential

open access: yesCarbohydrate Polymer Technologies and Applications
Chondroitin sulfate is an anionic glycosaminoglycan derived from animal and marine sources, as well as synthesized in the human body and by microbes.
Syed Muhammad Ahmad   +7 more
doaj   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

Investigating the Role of Aggrecan in Intervertebral Disc Degeneration [PDF]

open access: yes, 2018
Low back pain affects nearly 85% of the population of the United States, and is associated with a huge socioeconomic burden. One of the leading causes of low back pain is Intervertebral Disc (IVD) degeneration, which results in an ingrowth of blood ...
King, Brian
core  

The O-Serine Linkage in Peptides of Chondroitin 4- or 6-Sulfate

open access: hybrid, 1965
Bonnie Anderson   +2 more
openalex   +1 more source

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

open access: yesThe FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson   +10 more
wiley   +1 more source

Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan [PDF]

open access: yes, 2000
It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated.
Bellina, Isabella   +11 more
core  

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