Results 181 to 190 of about 72,228 (283)

Ciprofloxacin Treatment in Juvenile Mice Involves Neuronal Activation and Mimics Physical Features of Human Disease

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Tendinopathy is a complex, painful condition that affects up to 5% of the general population in their lifetime. Antibiotic treatment with fluoroquinolones has been associated with the onset of tendinopathy and tendon rupture. The mechanisms behind fluoroquinolone induced tendinopathy remain unclear. To probe activation of potentially causative
Nicole A. Chittim, Amro A. Hussien, Nicolo Dubacher, Gabor Matyas, Jess G. Snedeker   +4 more
wiley   +1 more source

Implantable Bioresorbable Scaffold with Fucosylated Chondroitin Sulfate as a Promising Device for Delayed Stimulation of Hematopoiesis. [PDF]

Mar Drugs
Anisimova NY, Rybalchenko OV, Martynenko NS, Rybalchenko GV, Lukyanova EA, Bilan MI, Usov AI, Kiselevskiy MV, Nifantiev NE.   +8 more
europepmc   +1 more source

Revisiting Hyaluronan Catabolism in Bacteroides: Pathway Conservation, Overlooked Proteins, and Predictive Accuracy

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Hyaluronan degradation in Bacteroides cannot be reliably predicted from canonical PL8/GH88 enzymes alone. Experimental validation reveals coordinated induction of noncanonical accessory proteins (BT4410/BT4411), highlighting pathway plasticity and context‐dependent glycosaminoglycan utilization. ABSTRACT The ability of gut microbes to degrade host‐ and
Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky, Gabriela Ambrozova, Lukas Kubala, Kristyna Turkova   +6 more
wiley   +1 more source

Chondroitin Sulfate and Proteinoids in Neuron Models. [PDF]

ACS Appl Bio Mater
Mougkogiannis P, Adamatzky A.
europepmc   +1 more source

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source

Effect of a chondroitin sulfate chain linked to the bikunin core peptide on gene expression in lipopolysaccharide-treated uterine cervical fibroblasts. [PDF]

Biochem Biophys Rep
Kurotaki S, Kakizaki I, Tanaka K, Tsushima R, Suto S, Tanaka S, Kodama T, Ito A, Takahashi R, Yokoyama Y.   +9 more
europepmc   +1 more source

Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang, Ruo‐Lan Shi, You‐Xia Huang, Li‐Ni Liu, Jia‐Sheng Tao, Xian‐Hui Li, Xiao‐Da Li   +6 more
wiley   +1 more source

Human Proteoglycan Linkage Region Glycosyltransferases are Dimeric and Show Unexpected Specificities

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Non‐canonical glycopeptides of the proteoglycan linkage region are accessible by the enzymes B3GalT6 and GlcAT‐1 confirming a recently discovered rescue mode in glycosaminoglycan (GAG) biosynthesis. The crystal structure of B3GalT6 revealed a covalent dimer linked by a disulfide. Abstract We selected the N,O‐glycosylated proteoglycan bikunin as a model
Sascha Weidler, Ole Bundgaard, Markus Hessefort, Marisa Rädisch, Christopher Günther Franz Graf, Kevin Lam, Vanessa J. Neubauer, Johanna Eisenreich, Leonhard Köhler, Kelley W. Moremen, Catharina Steentoft, Henrik Clausen, Teng‐Yi Huang, Shang‐Cheng Hung, Clemens Steegborn, Michael Weyand, Carlo Unverzagt   +16 more
wiley   +2 more sources

Chondroitin sulfate regulates proliferation of Drosophila intestinal stem cells. [PDF]

PLoS Genet
Knudsen C, Moriya A, Nakato E, Gulati R, Akiyama T, Nakato H.   +5 more
europepmc   +1 more source

Glucosamine Sulfate/Chondroitin Sulfate Tablet [PDF]

, 2020
openaire   +1 more source