Results 101 to 110 of about 54,015 (281)

“Teaching old dogs new tricks”: targeting neural extracellular matrix for normal and pathological aging-related cognitive decline

open access: yesNeural Regeneration Research, 2019
Cognitive decline is a feature of normal and pathological aging. As the proportion of the global aged population continues to grow, it is imperative to understand the molecular and cellular substrates of cognitive aging for therapeutic discovery.
Adam D Richard, Xiao-Hong Lu
doaj   +1 more source

Instant determination of the potential biomarker heparan sulfate in human plasma by a mix-and-read fluorescence assay [PDF]

open access: yesarXiv, 2017
Heparan sulfate (HS) is a linear, polydisperse sulfated polysaccharide belonging to the glycosaminoglycan family. HS proteoglycans are ubiquitously found at the cell surface and extracellular matrix in animal species. HS is involved in the interaction with a wide variety of proteins and the regulation of many biological activities.
arxiv  

Simultaneous localization of type II collagen and core protein of chondroitin sulfate proteoglycan in individual chondrocytes.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1979
In order to investigate the coordinated synthesis of matrix components by individual chondrocytes, specific antibodies to type I collagen, type II collagen, and chondroitin sulfate proteoglycan core protein were used in simultaneous double ...
B. Vertel, A. Dorfman
semanticscholar   +1 more source

Chondroitin sulfates and their binding molecules in the central nervous system [PDF]

open access: yes, 2017
Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in the central nervous system (CNS) matrix. Its sulfation and epimerization patterns give rise to different forms of CS, which enables it to interact specifically and with a ...
Djerbal, L, Kwok, JCF, Lortat-Jacob, H
core   +3 more sources

Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans

open access: yesJournal of Lipid Research, 1993
The association of plasma low density lipoproteins (LDL) with arterial proteoglycans (PG) is of key importance in LDL retention and modification in the artery wall.
IJ Edwards   +4 more
doaj  

CSPG4-dependent cytotoxicity for C. difficile TcdB is influenced by extracellular calcium and chondroitin sulfate

open access: yesmSphere
TcdB is an intracellular bacterial toxin indispensable to Clostridioides difficile infections. The ability to use chondroitin sulfate proteoglycan 4 (CSPG4) as a primary cell surface receptor is evolutionarily conserved by the two major variants of TcdB.
D. Annie Doyle   +2 more
doaj   +1 more source

Chondroitin sulfate proteoglycans from salmon nasal cartilage inhibit angiogenesis

open access: yesBiochemistry and Biophysics Reports, 2017
Because cartilage lacks nerves, blood vessels, and lymphatic vessels, it is thought to contain factors that inhibit the growth and development of those tissues.
Takashi Kobayashi   +3 more
doaj   +1 more source

Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury

open access: yesJournal of Neuroscience, 1994
Injury to the adult mammalian CNS results in reactive changes among the glial cells surrounding the site of damage. Recently, an unusual class of glial cells has been identified within the intact adult rat cerebellum on the basis of the expression of the
J. Levine
semanticscholar   +1 more source

Collagens in avian neural crest development: distribution in vivo and migration-promoting ability in vitro [PDF]

open access: yes, 1991
This study examines the spatiotemporal distribution of collagen (Col) types I-V and IX during neural crest development in vivo and their ability to support neural crest cell movement in vitro.
Bronner-Fraser, Marianne   +2 more
core  

Biochemical study of dermatan sulfate glycosaminoglycan in adult male patients with Nyhus type II inguinal hernia [PDF]

open access: yes, 2011
OBJECTIVE: To compare the amount of the dermatan sulfate glycosaminoglycan between male patients with Nyhus type II inguinal hernias and subjects without inguinal hernia, aged between 20 and 40 years.
Dreyfuss, Juliana Luporini   +5 more
core   +1 more source

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