Results 131 to 140 of about 54,015 (281)
Ultrasensitive quantification of dextran sulfate by a mix-and-read fluorescent probe assay [PDF]
arXiv, 2017 Dextran sulfate is semi-synthetic, polydisperse sulfated polysaccharide with important applications in clinical practice, in the manufacturing of plasma derived protein therapeutics and in biomedical research. The sensitive detection of dextran sulfate is relevant to preclinical and clinical drug development projects, the quality control of ...
arxiv
Journal of Cell Biology, 1989 Immunocytochemical methods were used at the levels of light and electron microscopy to examine the intracellular compartments of chondrocytes involved in extracellular matrix biosynthesis. The results of our studies provide morphological evidence for the
B. Vertel +4 more
semanticscholar +1 more source
Molecular cloning and sequence analysis of a chondroitin sulfate proteoglycan cDNA.
Proceedings of the National Academy of Sciences of the United States of America, 1985 We report the identification and DNA sequence of a chondroitin sulfate proteoglycan core protein cDNA. A cDNA clone, pPG1, was selected from a rat yolk sac tumor poly(A)+RNA-derived cDNA library by using synthetic oligonucleotides predicted from the NH2 ...
M. Bourdon +3 more
semanticscholar +1 more source
Mast cell carboxypeptidase A, a secretory granule component [PDF]
, 2005 Mast cells are highly granulated cells of the immune system that upon stimulation release a number of inflammatory mediators including heparin and/or chondroitin sulphate (CS) proteoglycan (PG) and various heparin-binding proteases such as tryptase ...
Henningsson, Frida
core
Quantification of sulfated polysaccharides in mouse and rat plasma by the Heparin Red mix-and-read fluorescence assay [PDF]
arXiv, 2017 Sulfated polysaccharides constitute a large and complex group of macromolecules which possess a wide range of important biological properties. Many of them hold promise as new therapeutics, but determination of their blood levels during pharmacokinetic studies can be challenging.
arxiv
Journal of Experimental Medicine, 1985 A clone of natural killer (NK) cells (JTB18) was found to be ultrastructurally similar to peripheral blood large granular lymphocytes (LGL). These cells incorporated [35S]sulfate into cell- associated proteoglycan molecules, which were then isolated by ...
R. P. MacDermott +10 more
semanticscholar +1 more source
Extracellular matrix alterations in the Peyronie’s disease
Journal of Advanced Research, 2017 Peyronie’s disease is characterized by fibrous plaque formation of the tunica albuginea, causing penile deformity and fertility problems. The aim of the present study was to investigate alterations in the extracellular matrix in Peyronie’s disease.
Marcelo Silva Watanabe +8 more
doaj +1 more source
Detection of Proteoglycan Loss from Articular Cartilage using Brillouin Microscopy, with Applications to Osteoarthritis [PDF]
arXiv, 2018 The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan(PG), leading to an increase in tissue hydration and permeability.
arxiv
Journal of Immunology, 1985 As a first step to elucidating the role of the Ia-associated chondroitin sulfate proteoglycan (CSPG) in the biology of the Ia antigens, we have studied several aspects of the interactions of the CSPG with the Ia/invariant chain glycoproteins.
A. Sant, S. Cullen, B. Schwartz
semanticscholar +1 more source
iScience, 2023 Summary: Biglycan (BGN) is a proteoglycan with branch chains and highly expressed in enteric neurons in the tumor tissue of colorectal cancer (CRC), which is negatively associated with survival rates in patients with CRC.
Yuyu Xu +11 more
doaj