Results 261 to 270 of about 54,015 (281)
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Chondroitin sulfate proteoglycans as mediators of axon growth and pathfinding
Cell and Tissue Research, 1997This review focuses primarily on studies concerning the potential roles of two nervous-tissue-specific chondroitin sulfate proteoglycans, viz., neurocan and phosphacan, in cell interactions and neurite growth in the developing central nervous system.
Richard U. Margolis, Renée K. Margolis
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Expression of chondroitin sulfate proteoglycans in the chiasm of mouse embryos
The Journal of Comparative Neurology, 2000Chondroitin sulfate (CS) proteoglycans have been implicated as molecules that are involved in axon guidance in the developing neural pathways. The spatiotemporal expression of CS was investigated in the developing retinofugal pathway in mouse embryos by using the CS-56 antibody.
Shum, DKY, Chan, SO, Chung, KY
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Interaction of Proteoglycans and Chondroitin Sulfates with Calcium or Phosphate Ions
Canadian Journal of Biochemistry, 1971Equilibrium dialysis was used to study the distribution of calcium or phosphate ions at equilibrium in dialysis cells containing proteoglycan or chondroitin sulfate in one compartment. A higher concentration of calcium or lower concentration of phosphate was found in the cell compartment containing the polymer than in the compartment separated from it
J. M. Bowness, E. A. MacGregor
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Chondroitin sulfate proteoglycan of human leukocytes
Biochimica et Biophysica Acta (BBA) - General Subjects, 1969Abstract 1. 1. A chondroitin sulfate proteogylcan was isolated from leukocyte granules and partly characterized. It had a low protein content and a relatively low molecular size. 2. 2. The incorporation of [ 35 S]sulfate, [ 14 C]glucosamine and [ 3 H]serine into chondroitin sulfate was inhibited by puromycin, indicating that the elongation of
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Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination
Annals of Neurology, 2012AbstractObjective:Failure of remyelination is a critical impediment to recovery in multiple sclerosis (MS). Chondroitin sulfate proteoglycans (CSPGs) have been reported to accumulate in MS lesions, and we thus examined the functional roles of CSPGs on oligodendrocyte precursor cells (OPCs), oligodendrocytes, and remyelination.Methods:We evaluated the ...
V. Wee Yong +8 more
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The role of chondroitin sulfate proteoglycans in remyelination
2011Includes copy of animal protocol approval. Original copy with original Partial Copyright Licence.
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Structure, Metabolism, and Tissue Roles of Chondroitin Sulfate Proteoglycans
2006Publisher Summary Proteoglycans (PGs) are a complex group of glycoproteins that are characterized by the presence of one or more sulfated glycosaminoglycan (GAG) chains and various oligosaccharides that are covalently attached to a core protein. The majority of chondroitin sulfate proteoglycans (CSPGs) belongs to the group of large aggregating PGs ...
Handley, Christopher. +2 more
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From barriers to bridges: chondroitin sulfate proteoglycans in neuropathology
Trends in Molecular Medicine, 2006Emerging studies have revealed new roles for the neural extracellular matrix in neuropathologies. The structure of this matrix is unusual and uniquely enriched in chondroitin sulfate proteoglycans, particularly those of the lectican family. Historically, lecticans have attracted considerable interest in the normal and injured brain for their prominent ...
Russell T. Matthews, Mariano S. Viapiano
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Identification and Immunolocalization of Chondroitin Sulfate Proteoglycans in Tooth Cementum
Connective Tissue Research, 1999Proteoglycans (PGs) display a great diversity in their core proteins as well as carbohydrate structures and are thought to be involved in many biological functions. Recently we have identified and immunolocalized two keratan sulfate PGs, fibromodulin and lumican, in bovine tooth cementum (Cheng et al., Connect. Tissue Res. 34: 87-96, 1996).
Bruce Caterson +2 more
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Journal of the National Cancer Institute, 1983
Anchorage-independent growth of tumor cells constitutes a phenotype highly associated with malignant transformation and appears to be important in the ultimate event of tumor metastasis, i.e., secondary tumor colonization.
J. Harper, R. Reisfeld
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Anchorage-independent growth of tumor cells constitutes a phenotype highly associated with malignant transformation and appears to be important in the ultimate event of tumor metastasis, i.e., secondary tumor colonization.
J. Harper, R. Reisfeld
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