Results 21 to 30 of about 43,424 (239)

Glycogenes in Oncofetal Chondroitin Sulfate Biosynthesis are Differently Expressed and Correlated With Immune Response in Placenta and Colorectal Cancer

Frontiers in Cell and Developmental Biology, 2021
Oncofetal chondroitin sulfate expression plays an important role in the development of tumors and the pathogenesis of malaria in pregnancy. However, the biosynthesis and functions of these chondroitin sulfates, particularly the tissue-specific regulation
Zi-Yi Wu, Yong-Qiao He, Tong-Min Wang, Da-Wei Yang, Dan-Hua Li, Chang-Mi Deng, Lian-Jing Cao, Jiang-Bo Zhang, Wen-Qiong Xue, Wei-Hua Jia, Wei-Hua Jia   +10 more
doaj   +1 more source

Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats. [PDF]

PLoS ONE, 2010
BACKGROUND: Chronic transplant dysfunction explains the majority of late renal allograft loss and is accompanied by extensive tissue remodeling leading to transplant vasculopathy, glomerulosclerosis and interstitial fibrosis. Matrix proteoglycans mediate
Heleen Rienstra, Kirankumar Katta, Johanna W A M Celie, Harry van Goor, Gerjan Navis, Jacob van den Born, Jan-Luuk Hillebrands   +6 more
doaj   +1 more source

Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection

Nature Communications, 2021
Chondroitin sulfate proteoglycan 4 (CSPG4) is a potential receptor for C. difficile toxin B (TcdB) during C. difficile infections (CDIs). Here, the cryo-EM structure of a TcdB–CSPG4 complex and CDI mouse models offer insights into CSPG4 role in CDIs and ...
Peng Chen, Ji Zeng, Zheng Liu, Hatim Thaker, Siyu Wang, Songhai Tian, Jie Zhang, Liang Tao, Craig B. Gutierrez, Li Xing, Ralf Gerhard, Lan Huang, Min Dong, Rongsheng Jin   +13 more
doaj   +1 more source

Ultraviolet irradiation induces the accumulation of chondroitin sulfate, but not other glycosaminoglycans, in human skin. [PDF]

PLoS ONE, 2011
Ultraviolet (UV) light alters cutaneous structure and function. Prior work has shown loss of dermal hyaluronan after UV-irradiation of human skin, yet UV exposure increases total glycosaminoglycan (GAG) content in mouse models.
Benjamin Boegel Werth, Muhammad Bashir, Laura Chang, Victoria P Werth   +3 more
doaj   +1 more source

Effects of sesamin on chondroitin sulfate proteoglycan synthesis induced by interleukin-1beta in human chondrocytes. [PDF]

BMC Complement Altern Med, 2017
Srisuthtayanont W, Pruksakorn D, Kongtawelert P, Pothacharoen P.   +3 more
europepmc   +3 more sources

Selection of novel affinity-matured human chondroitin sulfate proteoglycan 4 antibody fragments by yeast display. [PDF]

Protein Eng Des Sel, 2017
Yu X, Qu L, Bigner DD, Chandramohan V.
europepmc   +3 more sources

Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans

Journal of Lipid Research, 1993
The association of plasma low density lipoproteins (LDL) with arterial proteoglycans (PG) is of key importance in LDL retention and modification in the artery wall.
IJ Edwards, IJ Goldberg, JS Parks, H Xu, WD Wagner   +4 more
doaj   +1 more source

Binding of a Large Chondroitin Sulfate/Dermatan Sulfate Proteoglycan, Versican, to L-selectin, P-selectin, and CD44*

Journal of Biological Chemistry, 2000
Here we show that a large chondroitin sulfate proteoglycan, versican, derived from a renal adenocarcinoma cell line ACHN, binds L-selectin, P-selectin, and CD44.
H. Kawashima, M. Hirose, J. Hirose, D. Nagakubo, A. Plaas, M. Miyasaka   +5 more
semanticscholar   +1 more source

Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

Nature Communications, 2017
Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller ...
Stefanie G. Wohl, Nikolas L. Jorstad, Edward M. Levine, Thomas A. Reh   +3 more
doaj   +1 more source

Glypican-1, Phosphacan/Receptor Protein-Tyrosine Phosphatase-ζ/β and its Ligand, Tenascin-C, are Expressed by Neural Stem Cells and Neural Cells Derived from Embryonic Stem Cells

ASN Neuro, 2010
The heparan sulfate proteoglycan glypican-1, the chondroitin sulfate proteoglycan phosphacan/RPTP (receptor protein-tyrosine phosphatase)-ζ/β and the extracellular matrix protein tenascin-C were all found to be expressed by neural stem cells and by ...
Mary Abaskharoun, Marie Bellemare, Elizabeth Lau, Richard U Margolis   +3 more
doaj   +1 more source