Results 31 to 40 of about 54,015 (281)
Frontiers in Cell and Developmental Biology, 2021 Oncofetal chondroitin sulfate expression plays an important role in the development of tumors and the pathogenesis of malaria in pregnancy. However, the biosynthesis and functions of these chondroitin sulfates, particularly the tissue-specific regulation
Zi-Yi Wu +10 more
doaj +1 more source
The role of aggrecan in normal and osteoarthritic cartilage [PDF]
Journal of Experimental Orthopaedics, 2014 Aggrecan is a large proteoglycan bearing numerous chondroitin sulfate and keratan sulfate chains that endow articular cartilage with its ability to withstand compressive loads.
John S Mort, Peter J Roughley
core +2 more sources
Targeted downregulation of N‐acetylgalactosamine 4‐sulfate 6‐O‐sulfotransferase significantly mitigates chondroitin sulfate proteoglycan‐mediated inhibition [PDF]
Glia, 2011 Lohitash Karumbaiah +5 more
openalex +2 more sources
Nature Communications, 2021 Chondroitin sulfate proteoglycan 4 (CSPG4) is a potential receptor for C. difficile toxin B (TcdB) during C. difficile infections (CDIs). Here, the cryo-EM structure of a TcdB–CSPG4 complex and CDI mouse models offer insights into CSPG4 role in CDIs and ...
Peng Chen +13 more
doaj +1 more source
Statistical method for analysis of interactions between chosen protein and chondroitin sulfate in an aqueous environment [PDF]
, 2022 We present the statistical method to study the interaction between a chosen protein and another molecule (e.g., both being components of lubricin found in synovial fluid) in a water environment. The research is performed on the example of univariate time series of chosen features of the dynamics of mucin, which interact with chondroitin sulfate (4 and ...
arxiv +1 more source
Ultraviolet irradiation induces the accumulation of chondroitin sulfate, but not other glycosaminoglycans, in human skin. [PDF]
PLoS ONE, 2011 Ultraviolet (UV) light alters cutaneous structure and function. Prior work has shown loss of dermal hyaluronan after UV-irradiation of human skin, yet UV exposure increases total glycosaminoglycan (GAG) content in mouse models.
Benjamin Boegel Werth +3 more
doaj +1 more source
Glycosaminoglycans in the human cornea: age-related changes [PDF]
, 2015 AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia +6 more
core +2 more sources
Opticin Binds to Heparan and Chondroitin Sulfate Proteoglycans
Investigative Opthalmology & Visual Science, 2005 The extracellular matrix glycoprotein opticin is a small leucine-rich repeat proteoglycan/protein family member that was discovered associated with vitreous humor collagen fibrils. Opticin is present throughout the vitreous, but is particularly concentrated at the internal limiting lamina, where it colocalizes with type XVIII collagen.
Hindson, V. John +3 more
openaire +4 more sources
Cell Research, 2014 As a gram-positive, spore-forming anaerobic bacillus, Clostridium difficile (C. difficile) is responsible for severe and fatal pseudomembranous colitis, and poses the most urgent antibiotic resistance threat worldwide. Epidemic C.
Pengfei Yuan +13 more
semanticscholar +1 more source
Journal of Immunotherapy for Cancer, 2014 BackgroundThe development of immunotherapy has led to significant progress in the treatment of metastatic cancer, including the development of genetic engineering technologies that redirect lymphocytes to recognize and target a wide variety of tumor ...
R. Beard +11 more
semanticscholar +1 more source