Results 71 to 80 of about 54,015 (281)

Proteoglycan form of macrophage colony-stimulating factor binds low density lipoprotein [PDF]

, 1994
We recently isolated a proteoglycan form of macrophage colony-stimulating factor (PG-M-CSF) that carries a chondroitin sulfate glycosaminoglycan chain. Here, we examined the interaction of PG-M-CSF with low density lipoprotein (LDL).
Inaba T, Kawashima T, Kimura F, Kondo S, Machinami R, Motoyoshi K, Nagata N, Ohtsuki T, Oka T, Suzu S, Torikata C, Yamada N, Yanai N, 山田 信博   +13 more
core   +1 more source

Expanding the Chondroitin Sulfate Glycoproteome — But How Far?

Frontiers in Cell and Developmental Biology, 2021
Chondroitin sulfate proteoglycans (CSPGs) are found at cell surfaces and in connective tissues, where they interact with a multitude of proteins involved in various pathophysiological processes.
Fredrik Noborn, Mahnaz Nikpour, Andrea Persson, Jonas Nilsson, Jonas Nilsson, Göran Larson   +5 more
doaj   +1 more source

PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

Science, 2009
Toward Neuronal Regeneration Neurons in the central nervous system that are severed or crushed do not regenerate well. Part of the problem derives from the glial scars left behind after such damage.
Yingjie Shen, Alan P. Tenney, S. Busch, K. Horn, Fernando X. Cuascut, Kai-Fenp Liu, Zhigang He, J. Silver, J. Flanagan   +8 more
semanticscholar   +1 more source

Neuroendocrine tumors show altered expression of chondroitin sulfate, glypican 1, glypican 5 and syndecan 2 depending on their differentiation grade

Frontiers in Oncology, 2014
Neuroendocrine tumors are found throughout the body and are important as they give rise to distinct clinical syndromes. Glycosaminoglycans, in proteoglycan form or as free chains, play vital roles in every step of tumor progression.
Olivia eGarcía-Suárez, Beatriz eGarcía, Iván eFernández-Vega, Aurora eAstudillo, Aurora eAstudillo, Luis M Quirós, Luis M Quirós   +6 more
doaj   +1 more source

Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan [PDF]

, 2000
It has been proposed that hyaluronan-binding proteoglycans play an important role as guiding cues during neural crest (NC) cell migration, but their precise function has not been elucidated.
Bellina, Isabella, Bronner-Fraser, Marianne, Colombatti, Alfonso, Doliana, Roberto, Iacopetti, Paola, Kimata, Koji, Löfberg, Jan, Mörgelin, Matthias, Perissinotto, Daniela, Perris, Roberto, Pettway, Zoé, Shinomura, Tamayuki   +11 more
core  

ADAMTS -1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes [PDF]

, 2006
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) enzymes are a recently described group of metalloproteinases. The substrates degraded by ADAMTS-1, -4 and -5 suggests that they play a role in turnover of extracellular matrix in the
A.K. Cross, Abbaszzade, Asher, Bandtlow, Buttini, C.J. Stock, Cardenas, Clark, Clausen, Collins-Racie, D.J. Buttle, Eddleston, G. Haddock, Hashimoto, Inatani, J. Surr, Jiang, Jones, Krekoski, Krupinski, Kuno, Kuno, Kurazono, Legos, M.N. Woodroofe, Medina-Flores, Miguel, Mulcahy, Nedergaard, Novak, Ohtaki, Pangalos, Pekny, Plumb, Porter, R.A.D. Bunning, Rawlings, Rhodes, Rosenberg, Rosenberg, Rothwell, S. Allan, Satoh, Smith, Sobel, Somerville, Tang, Tsuzaki, Vankemmelbeke, Vazquez, Wang, Yamaguchi, Yu   +52 more
core   +1 more source

Contributions of chondroitin sulfate proteoglycans to neurodevelopment, injury, and cancer [PDF]

Current Opinion in Neurobiology, 2014
Chondroitin sulfate proteoglycans (CSPGs) are a diverse family of extracellular matrix (ECM) molecules that make significant contributions to the patterning and routing of migrating neural cells and extending axons. Three distinct modes of migration mediation result from the relative abundance and positioning of expressed CSPGs, the profile of CSPG ...
Jerry Silver, Daniel J. Silver
openaire   +2 more sources

Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors

Journal of Neuroscience, 2011
Chondroitin sulfate proteoglycans (CSPGs) are a family of extracellular matrix molecules with various functions in regulating tissue morphogenesis, cell division, and axon guidance.
D. Fisher, B. Xing, J. Dill, Hui Li, H. Hoang, Zhenze Zhao, Xiao-li Yang, R. Bachoo, Stephen Cannon, F. Longo, M. Sheng, J. Silver, Shuxin Li   +12 more
semanticscholar   +1 more source

Glycans and glycosaminoglycans in neurobiology: key regulators of neuronal cell function and fate [PDF]

, 2018
The aim of the present study was to examine the roles of l-fucose and the glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate (CS/DS) with selected functional molecules in neural tissues.
Hayes, Anthony J., Melrose, James
core   +2 more sources

Chondroitin Sulfate Proteoglycans Are Associated with the Lesions of Alzheimer's Disease

Experimental Neurology, 1993
Chondroitin sulfate proteoglycans (CSPG) are extracellular matrix proteins inhibitory to neurite outgrowth in vitro and correlated with decreased neurite outgrowth after CNS injury. Previously, heparan sulfate proteoglycan and dermatan sulfate proteoglycan have been shown to be associated with senile plaques (SPs) and neurofibrillary tangles (NFTs) but
Dewitt, David A., Silver, Jerry, Canning, David R., Perry, George   +3 more
openaire   +5 more sources