Results 81 to 90 of about 54,015 (281)
Biophysical and biomechanical properties of cartilage [PDF]
arXiv, 2023 Cartilage is a connective tissue that covers the surfaces of bones in joints and provides a smooth gliding surface for movement. It is characterized by specific biophysical properties that allow it to withstand compressive loads, distribute mechanical forces, and maintain tissue integrity.
arxiv
Molecular Cancer, 2010 BackgroundAdvanced melanoma is characterized by a pronounced resistance to therapy leading to a limited patient survival of ~6 - 9 months. Here, we report on a novel bifunctional therapeutic fusion protein, designated anti-MCSP:TRAIL, that is comprised ...
M. de Bruyn +8 more
semanticscholar +1 more source
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]
, 2005 Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
core +2 more sources
Inhibition and enhancement of neural regeneration by chondroitin sulfate proteoglycans
Neural Regeneration Research, 2017 The current dogma in neural regeneration research implies that chondroitin sulfate proteoglycans (CSPGs) inhibit plasticity and regeneration in the adult central nervous system (CNS). We argue that the role of the CSPGs can be reversed from inhibition to activation by developmentally expressed CSPG-binding factors.
Rauvala, Heikki +3 more
openaire +5 more sources
Heparan sulfate proteoglycan-dependent neutrophil chemotaxis toward PR-39 cathelicidin
Journal of Inflammation, 2006 Cathelicidins are mammalian proteins containing a C-terminal cationic antimicrobial domain. Porcine PR-39 cathelicidin affects leukocyte biology.
Patsch Josef R +6 more
doaj +1 more source
Geochemistry constrains global hydrology on Early Mars [PDF]
, 2019 Ancient hydrology is recorded by sedimentary rocks on Mars. The most voluminous sedimentary rocks that formed during Mars' Hesperian period are sulfate-rich rocks, explored by the $Opportunity$ rover from 2004-2012 and soon to be investigated by the $Curiosity$ rover at Gale crater.
arxiv +1 more source
Damage in porous media due to salt crystallization [PDF]
Physical Review E: Statistical, Nonlinear, and Soft Matter Physics
81 (2010) 066110, 2010 We investigate the origins of salt damage in sandstones for the two most common salts: sodium chloride and sulfate. The results show that the observed difference in damage between the two salts is directly related to the kinetics of crystallization and the interfacial properties of the salt solutions and crystals with respect to the stone. We show that,
arxiv +1 more source
Chondroitin Sulfate and Heparan Sulfate Proteoglycans of PC12 Pheochromocytoma Cells
Journal of Biological Chemistry, 1989 We have isolated and characterized the cell-associated and secreted proteoglycans synthesized by a clonal line of rat adrenal medullary PC12 pheochromocytoma cells, which have been extensively employed for the study of a wide variety of neurobiological processes. Chondroitin sulfate accounts for 70-80% of the [35S] sulfate-labeled proteoglycans present
Richard U. Margolis +3 more
openaire +3 more sources
Congenital Disorders of Deficiency in Glycosaminoglycan Biosynthesis
Frontiers in Genetics, 2021 Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, and heparan sulfate are covalently attached to specific core proteins to form proteoglycans, which are distributed at the cell surface as well as in the extracellular matrix ...
Shuji Mizumoto, Shuhei Yamada
doaj +1 more source
Cells, 2021 Chondroitin sulfate (CS) is a major component of the extracellular matrix found to be abnormally accumulated in several types of cancer tissues. Previous studies have indicated that CS synthases and modification enzymes are frequently elevated in human ...
Yin-Hung Chu +5 more
doaj +1 more source