Results 1 to 10 of about 43,328 (269)

Gadd45β expression in chondrosarcoma: A pilot study for diagnostic and biological implications in histological grading [PDF]

Diagnostic Pathology, 2010
Background Although the diagnosis of chondrosarcoma, especially the distinction between enchondroma and low-grade chondrosarcoma or low-grade chondrosarcoma and high-grade chondrosarcoma, is pathologically difficult, differential diagnosis is very ...
Ishido Yasuhiro, Yamamoto Takuya, Nagano Satoshi, Yokouchi Masahiro, Sakakima Harutoshi, Tanimoto Akihide, Zenmyo Michihisa, Komiya Setsuro, Ijiri Kosei   +8 more
doaj   +2 more sources

Core needle biopsy of periacetabular chondrosarcoma often results in undergrading but does not change management by experienced orthopaedic oncologists. [PDF]

Sci Rep
Harvard H, Badejo MA, Levine N, Cantor N, Visgauss J, Brigman B, Eward WC.   +6 more
europepmc   +3 more sources

EZH2/hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression

eLife, 2023
Chondrosarcomas are primary cancers of cartilaginous tissue and capable of alteration to highly aggressive, metastatic, and treatment-refractory states, leading to a poor prognosis with a five-year survival rate at 11 months for dedifferentiated subtype.
Zong-Shin Lin, Chiao-Chen Chung, Yu-Chia Liu, Chu-Han Chang, Hui-Chia Liu, Yung-Yi Liang, Teng-Le Huang, Tsung-Ming Chen, Che-Hsin Lee, Chih-Hsin Tang, Mien-Chie Hung, Ya-Huey Chen   +11 more
doaj   +1 more source

High-Resolution Secretome Analysis of Chemical Hypoxia Treated Cells Identifies Putative Biomarkers of Chondrosarcoma

Proteomes, 2022
Chondrosarcoma is the second most common bone tumor, accounting for 20% of all cases. Little is known about the pathology and molecular mechanisms involved in the development and in the metastatic process of chondrosarcoma. As a consequence, there are no
Donatella Pia Spanò, Simone Bonelli, Matteo Calligaris, Anna Paola Carreca, Claudia Carcione, Giovanni Zito, Aldo Nicosia, Sergio Rizzo, Simone Dario Scilabra   +8 more
doaj   +1 more source

Mice with Trp53 and Rb1 deficiency in chondrocytes spontaneously develop chondrosarcoma via overactivation of YAP signaling

Cell Death and Disease, 2022
Chondrosarcoma (CHS) is a rare type of soft sarcoma with increased production of cartilage matrix arising from soft bone tissues. Currently, surgical resection is the primary clinical treatment for chondrosarcoma due to the poor response to radiotherapy ...
Yang Li, Shuting Yang, Yang Liu, Shuying Yang   +3 more
doaj   +1 more source

Mesenchymal chondrosarcoma of the mandible: A case report

Journal of Craniomaxillofacial Research, 2021
Mesenchymal chondrosarcoma as an aggressive type of chondrosarcoma shows a characteristic biphasic histopathologic pattern. The head and neck region is included a high proportion of extra skeletal sites. Very rare examples of Mesenchymal Chondrosarcoma
Samira Derakhshan, Sedigheh Rahrotaban, Samaneh Shirani, Shima Abbasi   +3 more
doaj   +1 more source

Visfatin-Induced Inhibition of miR-1264 Facilitates PDGF-C Synthesis in Chondrosarcoma Cells and Enhances Endothelial Progenitor Cell Angiogenesis

Cells, 2022
New treatments for chondrosarcoma are extremely important. Chondrosarcoma is a primary malignant bone tumor with a very unfavorable prognosis. High-grade chondrosarcoma has a high potential to metastasize to any organ in the body. Platelet-derived growth
Chang-Yu Song, Sunny Li-Yun Chang, Chih-Yang Lin, Chun-Hao Tsai, Shang-Yu Yang, Yi-Chin Fong, Yu-Wen Huang, Shih-Wei Wang, Wei-Cheng Chen, Chih-Hsin Tang   +9 more
doaj   +1 more source

WISP-3 Stimulates VEGF-C-Dependent Lymphangiogenesis in Human Chondrosarcoma Cells by Inhibiting miR-196a-3p Synthesis

Biomedicines, 2021
Chondrosarcoma is a malignant bone tumor with high metastatic potential. Lymphangiogenesis is a critical biological step in cancer metastasis. WNT1-inducible signaling pathway protein 3 (WISP-3) regulates angiogenesis and facilitates chondrosarcoma ...
Chih-Yang Lin, Shih-Wei Wang, Jeng-Hung Guo, Huai-Ching Tai, Wen-Chun Sun, Cheng-Ta Lai, Chen-Yu Yang, Shih-Chia Liu, Yi-Chin Fong, Chih-Hsin Tang   +9 more
doaj   +1 more source

Clinical Statistical Analysis with Comparison between Pelvic and Non-pelvic Chondrosarcoma

Oman Medical Journal, 2021
Objectives: Chondrosarcomas are rare tumors with a variable biological characteristic. Their treatment clinically and surgically is controversial. Analysis of the clinical statistics and prognostic factors of pelvic chondrosarcoma provides a reference ...
Sayed Abdulla Jami, Shi Jiandang, Brotendu Shekhar Roy, Zhanwen Zhou, Liu Chang Hao   +4 more
doaj   +2 more sources

Long-term follow-up after cervical en bloc resection as salvage surgery of spinal chondrosarcoma: illustrative case. [PDF]

J Neurosurg Case Lessons
Ott S, Schroeder M, Frosch KH, Hansen-Algenstaedt N.   +3 more
europepmc   +3 more sources