Results 31 to 40 of about 20,687 (197)

High‐Resolution Genomic Characterization of WAGR Spectrum Disorder: Insights From a Novel Cohort and Literature Synthesis, and Validation of Patient‐Reported Data

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT WAGR spectrum disorder (WAGRSD) is an ultra‐rare congenital disorder caused by heterozygous deletion of chromosome 11p13. While classically associated with Wilms tumor, Aniridia, Genitourinary anomalies, and a Range of developmental delays, accurate delineation of the deletion is critical for prognosis because the phenotypic spectrum extends ...
Andrew M. George, Bamelak T. Duki, Zoe S. Katz, Aravind Viswanathan, Suzanne P. MacFarland, Evan R. Hathaway, Caitlin Monahan, John Morris, Kelly L. Trout, Shari M. Krantz, Arupa Ganguly, Jennifer M. Kalish   +11 more
wiley   +1 more source

Expression of Aurora Kinase A and B in chondrosarcoma and its relationship with the prognosis

Diagnostic Pathology, 2012
Purpose To investigate the expression of Aurora Kinase A and B in patients with chondrosarcoma and consider it as a prognostic marker and molecular target of therapy.
Liang Xiaohui, Wang Danying, Wang Yan, Zhou Zhiqiang, Zhang Juan, Li Jinsong   +5 more
doaj   +1 more source

Multi-modality management of chondrosarcoma of scapula: A case report and review of literature

Cancer Treatment and Research Communications, 2023
Chondrosarcoma are malignant tumours in which neoplastic cells produce cartilage. The most commonly affected sites are pelvis, femur, humerus and ribs. Scapula involvement is relatively rare.
Ramakant Tiwari, Bharti Devnani, Balamurugan Thirunavukkarasu, Puneet Pareek, Prateek Daga, Amit Kumar   +5 more
doaj   +1 more source

Endoscopic Resection of Exostosis at the Medial Border of Scapula

Arthroscopy Techniques, EarlyView.
Abstract Scapular exostoses are rare, and ventral lesions are more common than dorsal lesions. Scapular exostoses can cause symptoms including pain and mechanical crepitus due to scapulothoracic bursitis, decreased active range of motion, “pseudowinging” of the scapula and snapping scapula.
Tun Hing Lui, Florence Ou Suet Pang
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Chondrosarcoma of the Heart

The Korean Journal of Thoracic and Cardiovascular Surgery, 2015
Chondrosarcoma is a rare entity of malignant tumor which arises from cartilaginous tissue, and the literatures on this disease are scarce. The first-line of treatment for cardiac chondrosarcoma is surgery. Due to early local recurrence and distant metastasis, the prognosis is poor even after complete surgical excision.
Kim, Do Jung, Wi, Jin Hong, Kim, Yonhee, Lee, Sak, Joo, Hyun-Chel, Youn, Young-Nam   +5 more
openaire   +3 more sources

Testicular chondrosarcoma

Urology Annals, 2021
Only 5% of all urological tumors are accounted as Testicular tumors. Furthermore, a well differentiated chondrosarcoma of the testis is extremely rare. Thus, we are representing a rare case of testicular chondrosarcoma. A 43-year-old male with right scrotal swelling did Doppler Ultrasonography demonstrating a large heterogenous hypervascular mass ...
Abdulaziz Alhussaini, Mohammed Al Mansour, Noura Al Oudah, Khalid Al Rabeeah, Abdullah Al Khayal, Saad Abumelha   +5 more
openaire   +3 more sources

Apparent diffusion coefficient and arterial spin labeling perfusion of conventional chondrosarcoma in the parafalcine region: a case report

Radiology Case Reports, 2018
Intracranial chondrosarcoma is a very rare malignant tumor of the central nervous system, and is difficult to preoperatively distinguish from other tumors using conventional imaging techniques.
Daigo Kojima, MD, Takaaki Beppu, MD, Hiroaki Saura, MD, Yuichi Sato, MD, Shunrou Fujiwara, MD, Kuniaki Ogasawara, MD   +5 more
doaj   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

Head &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su, Matheus Sewastjanow‐Silva, Jack Phan, Marc‐Elie Nader, Shaan M. Raza, Franco DeMonte, Paul W. Gidley, Ehab Y. Hanna, Loretta A. Williams   +8 more
wiley   +1 more source