Results 21 to 30 of about 35,110 (238)

Elevated levels of Dickkopf-1 are associated with β-catenin accumulation and poor prognosis in patients with chondrosarcoma. [PDF]

PLoS ONE, 2014
BACKGROUND: Dickkopf-1 (DKK1) is an antagonist of Wnt/β-catenin signaling implicated in tumorigenesis. However, the biological role of DKK1 and β-catenin involved in chondrosarcoma has not been sufficiently investigated.
Changbao Chen, Hua Zhou, Xiaolin Zhang, Xinlong Ma, Zhongjun Liu, Xiaoguang Liu   +5 more
doaj   +1 more source

Physical Function and Quality of Life After Resection of Mobile Spine Chondrosarcoma. [PDF]

, 2019
Study Design:Retrospective cohort study. Objectives:(1) To assess patient-reported outcomes-physical function, pain, and quality of life-in patients who underwent resection of a mobile spine chondrosarcoma.
Chen, Yen-Lin E, DeLaney, Thomas F, Hartveldt, Stefan, Hornicek, Francis J, Janssen, Stein J, Paulino Pereira, Nuno Rui, Schwab, Joseph H, Stoop, Nicky   +7 more
core   +1 more source

Gadd45β expression in chondrosarcoma: A pilot study for diagnostic and biological implications in histological grading

Diagnostic Pathology, 2010
Background Although the diagnosis of chondrosarcoma, especially the distinction between enchondroma and low-grade chondrosarcoma or low-grade chondrosarcoma and high-grade chondrosarcoma, is pathologically difficult, differential diagnosis is very ...
Ishido Yasuhiro, Yamamoto Takuya, Nagano Satoshi, Yokouchi Masahiro, Sakakima Harutoshi, Tanimoto Akihide, Zenmyo Michihisa, Komiya Setsuro, Ijiri Kosei   +8 more
doaj   +1 more source

Prognostic Factors in Dedifferentiated Chondrosarcoma: A Retrospective Analysis of a Large Series Treated at a Single Institution. [PDF]

, 2019
Background:Dedifferentiated chondrosarcomas (DDCSs) are highly malignant tumors with a dismal prognosis and present a significant challenge in clinical management.
Chebib, Ivan, Chen, Yen-Lin E, Choy, Edwin, Cote, Gregory M, DeLaney, Thomas F, Deshpande, Vikram, Hornicek, Francis J, Miao, Ruoyu, Nielsen, Gunnlaugur Petur, Raskin, Kevin A, Schwab, Joseph H   +10 more
core   +1 more source

Advanced chondrosarcoma of the pelvis: a rare case of urinary obstruction [PDF]

, 2019
Chondrosarcoma is the second most common malignant tumor of the bone with an incidence of 1 in 200.000 per year. Axial skeleton is frequently involved showing poorer oncological outcomes than appendicular one: human pelvis is a site predilection.
Annoscia, Scipio, Bellei, Luca, De, Lucafracesco, Fortunati, Valentina, Manzi, Emy, Massarelli, Massimo, Maurizi, Angela, Olivieri, Valerio, Ollino, Massimo   +8 more
core   +1 more source

Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?

Case Reports in Oncological Medicine, 2021
Background. Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% and 2.5% of all chondrosarcoma. They are known to be chemo- and radiotherapy resistant; surgical resection is therefore the therapy of choice ...
Paulien West, Celine Jacobs, Michael Saerens, David Creytens, Gwen Sys, Lore Lapeire   +5 more
doaj   +1 more source

Laryngeal Chondrosarcoma [PDF]

Head and Neck Pathology, 2013
Laryngeal chondrosarcoma is a rare tumor requiring clinical, histologic, and radiographic correlation for definitive diagnosis. Although it typically presents with low-grade histology, even high-grade histology has a fairly indolent progression in this location, with a relatively low-likelihood for metastatic potential or recurrence.
Evelyn M, Potochny, Aaron R, Huber
openaire   +2 more sources

An improved protocol for small RNA library construction using High Definition adapters [PDF]

, 2015
Next generation sequencing of small RNA (sRNA) libraries is widely used for studying sRNAs in various biological systems. However, cDNA libraries of sRNAs are biased for molecules that are ligated to adapters more or less efficiently than other molecules.
Aravin, Baran, Bushati, Edgar, Git, Hafner, He, Jagadeeswaran, Jayaprakash, Kawano, Mallory, Mortazavi, Munafó, Pease, Prüfer, Raabe, Reddy, Song, Sorefan, Stocks, Sun, Szittya, Szittya, Tian, Vigneault, Viollet, Willenbrock, Zhang, Zhuang   +28 more
core   +1 more source

Testicular chondrosarcoma [PDF]

International braz j urol, 2003
A case of primary chondrosarcoma of the testis is reported. A 40-year-old man presented a painless swelling of the right testis that he has been observing for 3 years. Gross examination of the resected specimen showed an encapsulated, gray to tan colored, roughly rounded tumor. Histologically, the tumor revealed a well-differentiated chondrosarcoma.
Yalçinkaya, Ulviye, Filiz, Gülaydan
openaire   +5 more sources

A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival

Journal of Bone Oncology, 2019
Chondrosarcomas are malignant cartilage tumors that are relatively resistant towards conventional therapeutic approaches. Kinase inhibitors have been investigated and shown successful for several different cancer types.
Yvonne de Jong, Fairuz Bennani, Jolieke G. van Oosterwijk, Gaia Alberti, Zuzanna Baranski, Pauline Wijers-Koster, Sanne Venneker, Inge H. Briaire-de Bruijn, Brendy E. van de Akker, Hans Baelde, Anne-Marie Cleton-Jansen, Bob van de Water, Erik H.J. Danen, Judith V.M.G. Bovée   +13 more
doaj   +1 more source