Results 21 to 30 of about 36,516 (242)
Prognostic importance of IDH mutations in chondrosarcoma: An individual patient data meta‐analysis
Cancer Medicine, 2021 IDH1/2 mutations are prevalent in cartilaginous tumors including chondrosarcoma. This meta‐analysis using individual patient data (IPD) aimed to investigate the clinical and prognostic association of these mutations in chondrosarcoma patients.
H. Vuong, T. Ngo, I. Dunn
semanticscholar +1 more source
Clinical Statistical Analysis with Comparison between Pelvic and Non-pelvic Chondrosarcoma
Oman Medical Journal, 2021 Objectives: Chondrosarcomas are rare tumors with a variable biological characteristic. Their treatment clinically and surgically is controversial. Analysis of the clinical statistics and prognostic factors of pelvic chondrosarcoma provides a reference ...
Sayed Abdulla Jami +4 more
doaj +2 more sources
Biomedicines, 2021 Chondrosarcoma is a malignant bone tumor with high metastatic potential. Lymphangiogenesis is a critical biological step in cancer metastasis. WNT1-inducible signaling pathway protein 3 (WISP-3) regulates angiogenesis and facilitates chondrosarcoma ...
Chih-Yang Lin +9 more
doaj +1 more source
Journal of Medical Imaging and Radiation Oncology, EarlyView., 2023 Summary Proton Beam Therapy (PBT) has the potential to improve paediatric cancer care by reducing radiation exposure and thus long‐term toxicities. Ethical concerns and debates surrounding the treatment, such as eligibility and accessibility, are ongoing in Australia. The Australian Bragg Centre for Proton Therapy and Research (ABCPTR) (named after Sir
Jeremy Khong +10 more
wiley +1 more source
TERT promoter mutation is an objective clinical marker for disease progression in chondrosarcoma
Modern Pathology, 2021 Chondrosarcomas are the second most common malignant bone tumor. Activating promoter mutations in telomerase reverse transcriptase (TERT) was recently described by us and others as a frequent mutation in high-grade chondrosarcoma.
Yifan Zhang +8 more
semanticscholar +1 more source
Metabolic Pathways and Targets in Chondrosarcoma
Frontiers in Oncology, 2021 Chondrosarcomas are the second most common primary bone malignancy. Chondrosarcomas are characterized by the production of cartilaginous matrix and are generally resistant to radiation and chemotherapy and the outcomes are overall poor.
I. Micaily +4 more
semanticscholar +1 more source
Cell Death and Disease, 2023 Chondrosarcoma is ineffective for conventional radiotherapy and chemotherapy with a poor prognosis. Hedgehog (Hh) signal pathway plays a crucial role in tumor growth and progression, which is constitutive activated in chondrosarcoma.
Yifeng Sun +4 more
doaj +1 more source
International Journal of Molecular Sciences, 2021 Chondrosarcoma is a malignant bone tumor that is characterized by high metastatic potential and marked resistance to radiation and chemotherapy. The knowledge that adipokines facilitate the initiation, progression, metastasis, and treatment resistance of
Shih-Ya Hung +10 more
semanticscholar +1 more source
Frontiers in Oncology, 2022 Chondrosarcoma is a common primary bone malignancy whose phenotype increases with its histologic grade. They are relatively resistant to chemotherapy and radiation therapy limiting curative options for disseminated disease.
Sjoerd P. F. T. Nota +10 more
doaj +1 more source
Clinical Orthopaedics and Related Research, 2021 Background Dedifferentiated chondrosarcoma is a chondrosarcoma subtype associated with high rates of recurrence and a poor prognosis. Others have proposed treatment of dedifferentiated chondrosarcoma using osteosarcoma protocols, including perioperative ...
L. Cranmer +10 more
semanticscholar +1 more source