Results 91 to 100 of about 43,328 (269)
Description of the immune microenvironment of chondrosarcoma and contribution to progression
Chondrosarcoma (CHS) is a rare bone malignancy characterized by its resistance to conventional systemic and radiation therapies. Whether immunotherapy targeting immune checkpoints may be active in these tumors remains unknown.
François A. Simard +7 more
doaj +1 more source
Background As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their
Boeuf Stephane +6 more
doaj +1 more source
ABSTRACT Aim Achieving maximal and safe tumour resection is a key goal in brain tumour surgery. Confocal laser endomicroscopy (CLE) enables real‐time visualisation of the tissue microstructure at a cellular level, potentially helping neurosurgeons distinguish non‐neoplastic from neoplastic tissue.
Ilona Iff +13 more
wiley +1 more source
The symptomatology of aneurysmal bone cyst : the value of diagnostic imaging [PDF]
Background: An aneurysmal bone cyst (ABC) is a benign lesion occurring mainly in children. Generally it is found in the metaphyses of long bones and in flat bones.
Bekiesińska-Figatowska, Monika +9 more
core
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Sinonasal Sarcomas Management: An International Consensus Statement
ABSTRACT Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.
Alessandro Vinciguerra +51 more
wiley +1 more source
Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra +9 more
wiley +1 more source
Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis; it has a poor prognosis and shows a predilection for metastasis to the lungs.
Chih-Yang Lin +6 more
doaj +1 more source
Chondrosarcoma of the temporomandibular joint : a case report and review of the literature [PDF]
Chondrosarcoma is a malignant tumor characterized by the formation of cartilage, but not bone, by tumor cells. Only 5% to 10% of chondrosarcomas occur in the head and neck, representing 0.1% of all head and neck neoplasms, with the larynx and the ...
Fresno Forcelledo, Manuel Florentino +3 more
core
Management of tracheal chondrosarcoma almost completely obstructing the airway: a case report [PDF]
Checklist and flow diagram.
Francesco Puma +3 more
core +2 more sources

