Results 91 to 100 of about 38,056 (264)

Chondrosarcoma of the Proximal Phalanx of the Fourth Digit: A Rare Location

Case Reports in Oncology, 2012
Introduction: Cartilaginous tumors involving the small bones of the hands and feet are usually benign such as enchondroma, chondromyxoid fibroma and chondroblastoma.
Thivi Vasilakaki, Aikaterini Tsavari, Evangelia Skafida, Kalliroi Koulia, Despina Myoteri, Xanthipi Grammatoglou, Alexandra Zisi, Nikolaos Firfiris, Kassiani Manoloudaki   +8 more
doaj   +1 more source

Chondrosarcoma: A Rare Misfortune in Aging Human Cartilage? The Role of Stem and Progenitor Cells in Proliferation, Malignant Degeneration and Therapeutic Resistance

International Journal of Molecular Sciences, 2018
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a peak incidence in adolescents and young adults, conventional and dedifferentiated chondrosarcomas mainly affect people in the 4th to 7th decade of life.
K. Boehme, S. Schleicher, F. Traub, B. Rolauffs   +3 more
semanticscholar   +1 more source

Pulmonary histiocytic sarcoma in an Indian crested porcupine (Hystrix indica) with suspected dissemination

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract An 11‐year‐old female Indian crested porcupine (Hystrix indica) presented with cough in December 2022. Initial diagnostic testing revealed neutrophilia, and radiographs revealed a bronchial pattern as well as significant enlargement of the left main bronchus.
Emily Cehrs
wiley   +1 more source

The role of dose escalation and proton therapy in perioperative or definitive treatment of chondrosarcoma and chordoma: An analysis of the National Cancer Data Base

Cancer, 2019
Chordomas and chondrosarcomas are a rare but challenging subset of tumors to treat; however, previous studies have shown benefits from proton therapy, which are thought to be primarily driven by prescription conformality permitting homogeneous tumor ...
R. Palm, D. Oliver, George Q. Yang, Yazan A. Abuodeh, A. Naghavi, P. Johnstone   +5 more
semanticscholar   +1 more source

Recent Advances in Enzymes and Chemoenzymatic Synthesis of Tetrasaccharide Linkage Region of Proteoglycans

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
The tetrasaccharide linkage region of proteoglycans is synthesized through a series of well‐controlled enzymatic reactions in nature. The expression, activity, and substrate profile of these biosynthetic enzymes and the latest development of chemoenzymatic synthesis of linkage region‐bearing glycopeptides are summarized in this review.
Po‐han Lin, Xuefei Huang
wiley   +1 more source

Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway

Journal of Bone Oncology, 2019
Background: Chondrosarcomas are malignant cartilage-producing tumors showing mutations and changes in gene expression in metabolism related genes. In this study, we aimed to explore the metabolome and identify targetable metabolic vulnerabilities in ...
Ruben D. Addie, Yvonne de Jong, Gaia Alberti, Alwine B. Kruisselbrink, Ivo Que, Hans Baelde, Judith V.M.G. Bovée   +6 more
doaj  

Novel therapeutic approaches in chondrosarcoma.

Future Oncology, 2017
Chondrosarcoma is a malignant tumor of bones, characterized by the production of cartilage matrix. Due to lack of effective treatment for advanced disease, the clinical management of chondrosarcomas is exceptionally challenging.
Genovefa Polychronidou, V. Karavasilis, S. Pollack, Paul H. Huang, Alexander Lee, Robin L. Jones   +5 more
semanticscholar   +1 more source

Does Resection of the Primary Tumor Improve Survival in Patients With Metastatic Chondrosarcoma?

Clinical Orthopaedics and Related Research, 2019
Background Although surgical resection or amputation has been the mainstay of localized chondrosarcoma management for many decades, its efficacy in patients with metastatic chondrosarcoma remains unknown, and likewise we do not know whether there are any
Kehan Song, Jian Song, Feiyan Chen, Kaiyuan Lin, Xiaosheng Ma, Jianyuan Jiang   +5 more
semanticscholar   +1 more source

Anti-miRNA Oligonucleotide Therapy for Chondrosarcoma

Molecular Cancer Therapeutics, 2019
Chondrosarcoma is a highly aggressive primary malignant bone tumor mostly occurring in adults. There are no effective systemic treatments, and patients with this disease have poor survival.
Xiao-juan Sun, Yupeng Chen, Hongchuan Yu, J. Machan, Ashna Alladin, J. Ramirez, R. Taliano, J. Hart, Qian Chen, R. Terek   +9 more
semanticscholar   +1 more source

Ensemble learning guided survival prediction and chemotherapy benefit analysis in high-grade chondrosarcoma: A study based on the surveillance, epidemiology, and end results (SEER) database

Journal of Orthopaedic Surgery
Purpose: The chemotherapy benefit for high-grade chondrosarcoma remains controversial. Ensemble learning has better overall performance than single computational approaches for clinical decision.
Xu Zheng, Longqiang Shu, Shanyi Lin, Hanqiang Jin, Xiaoyu Wang, Ting Yuan   +5 more
doaj   +1 more source