Abstract Osteosarcoma (OS) is an aggressive bone malignancy characterized by genomic instability and extensive extracellular matrix (ECM) remodeling. Members of the ADAMTS family are matrix‐associated proteases implicated in tumorigenesis; however, their roles in OS remain poorly defined. This study provides a comprehensive genomic, transcriptomic, and
Ehed Muhammed Aymaz +4 more
wiley +1 more source
Commentary on "a case of paratesticular leiomyosarcoma successfully treated with orchiectomy and chemotherapy" [PDF]
We have read with great interest the article written by Ko and colleagues on a particularly rare type of malignant mesenchymal tumor that is paratesticular leiomyosarcoma and we did appreciate the argumentation on the utility of adjuvant chemotherapy as ...
Marchetti, Paolo +3 more
core +1 more source
Juxtacortical chondrosarcoma [PDF]
The features are described of seven cases of "juxtacortical" chondrosarcoma, the term introduced by Jaffe for a rare but distinct entity and now accepted in the World Health Organisation classification as preferable to the term "periosteal" chondrosarcoma.
openaire +2 more sources
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
Intracortical Chondrosarcoma: a Case Report
Chondrosarcoma is the second most common primary mesenchymal malignant tumor of the bone. The most common form is central chondrosarcoma and the rarest is intracortical chondrosarcoma. Here, we describe the clinical, pathological, and imaging features of
Khodamorad Jamshidi +2 more
doaj
AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma [PDF]
Chemokine (C-C motif) ligand 3 (CCL3), also known as macrophage inflammatory protein-1α, is a cytokine involved in inflammation and activation of polymorphonuclear leukocytes. CCL3 has been detected in infiltrating cells and tumor cells.
Chih-Hsin Tang +5 more
core +1 more source
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Juxtacortical mandibular chondrosarcoma during pregnancy : a case report [PDF]
Chondrosarcoma is one of the most common malignant bone tumors in adults. It use to affect upper arm, pelvis and thigh bone. A wide surgical extirpation represent the gold standard to treat this disorder.
Cabello Serrano, Almudena +4 more
core +1 more source
Anterior Chest Wall Leiomyoma in a 4‐Year‐Old Girl: A Rare Pediatric Case
ABSTRACT Anterior chest wall leiomyoma is an exceptionally rare benign tumor in children. Complete surgical excision with appropriate chest wall reconstruction provides excellent outcomes, and histopathological confirmation including immunohistochemistry is essential to exclude malignancy.
Rajabu Athumani Bakari +9 more
wiley +1 more source
Identification of ZNF704 as a Novel Oncogene and an Independent Prognostic Marker in Chondrosarcoma
Changbao Chen,1 Hua Zhou,2 Xiaolin Zhang,1 Zhongjun Liu,2 Xinlong Ma1 1Department of Spinal Surgery, Tianjin Hospital, Tianjin, 300211, People’s Republic of China; 2Department of Orthopaedic Surgery, Peking University Third Hospital, Beijing ...
Chen C, Zhou H, Zhang X, Liu Z, Ma X
doaj

