Results 71 to 80 of about 36,516 (242)

Giant Chondrosarcoma of Proximal Humerus in an Adult Female Patient: A Case Report [PDF]

Malaysian Orthopaedic Journal, 2015
Chondrosarcoma is the third most common primary tumour of the bone, after myeloma and osteosarcoma. Most of the chondrosarcoma grow slowly and rarely metastasize, and they have an excellent prognosis after adequate surgery. However most of them are chemo
Ng CK, Azuhairy A, Tan LH, Nordin A
doaj   +1 more source

Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon, Laura M. Warmke, Ahmed K. Alomari, Rachel P. Kowal   +3 more
wiley   +1 more source

Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model. [PDF]

PLoS ONE, 2012
BACKGROUND: Chondrosarcomas are the second most frequent primary malignant type of bone tumor. No effective systemic treatment has been identified in advanced or adjuvant phases for chondrosarcoma.
Jennifer Perez, Anne Valérie Decouvelaere, Thomas Pointecouteau, Daniel Pissaloux, Jean Philippe Michot, Anthony Besse, Jean Yves Blay, Aurélie Dutour   +7 more
doaj   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

Histopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori, Alexander Guzzetta, Melissa Y. Tjota, Peng Wang, Tatjana Antic, Jung Woo Kwon   +5 more
wiley   +1 more source

Chondrosarcoma in a paediatric population: A study of 247 cases

Journal of Children's Orthopaedics, 2019
Purpose The aims of present study are to clarify the follow questions: 1) what constitutes paediatric chondrosarcoma?; 2) what are the effects of the demographic and tumour characteristics on survival in patients with paediatric chondrosarcoma?; 3) which
A.-M. Wu, G Li, J.-W. Zheng, C.-H. Chen, D Chen, Z.-G. Qiao, J.-G. Zhao, B Wang, W.-L. Fu, S.-R. Sheng, Y.-S. Wu, N.-F. Tian, Z.-K. Lin, H Xu   +13 more
doaj   +1 more source

Mesenchymal Chondrosarcoma Presenting as Atypical Brown–Sequard Syndrome

Annals of the Child Neurology Society, EarlyView.
Naman D. Shah, Adam Z. Kalawi, Rachel Pearson, Ali Nael, John R. Crawford   +4 more
wiley   +1 more source

Staying in the Unknown: Avoidance of Genetic Testing in Families With Hereditary Cancer Syndromes—A Qualitative Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach, Elizabeth E. Half, Hagit Baris‐Feldman, Anastasia Weis, Sharon Simchoni, Sue Kim, Maria C. Katapodi, Sivia Barnoy, Efrat Dagan   +8 more
wiley   +1 more source

Cytological diagnosis of chondrosarcoma: A case report with review of literature

Journal of the Scientific Society, 2015
Chondrosarcoma is a malignant tumor of bone showing cartilaginous differentiation. Fine needle aspiration cytology (FNAC) is found to be effective in the preoperative diagnosis of chondrosarcoma combined with radiological and clinical evaluation. Ribs is
Karuna Daswani, S Sudhamani, Ajita Pandit   +2 more
doaj   +1 more source

Application of Three‐Dimensionally Printed Surgical Guides in Precise Sacral Tumor Excision and Defect Reconstruction

Orthopaedic Surgery, EarlyView.
Patient‐specific 3D‐printed guiding templates significantly improve surgical precision and efficiency in complex sacral tumor resection and reconstruction compared to conventional freehand techniques. This computer‐assisted workflow reduces operative time, intraoperative blood loss, and fluoroscopy frequency, providing a safer, highly reproducible ...
Yansong Liu, Yinghua He, Huanwen Ding, Hu Chen, Zhongbiao Liang, Ningling Xie, Renxuan Tu, Qiang Tu   +7 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source