Results 41 to 50 of about 38,056 (264)

Non-Conventional Treatments for Conventional Chondrosarcoma

Cancers, 2020
Chondrosarcomas are the most common malignant tumors of the cartilage, are seen predominantly in adults, and have varied clinical behavior. The majority of them affect the medullary canal of long bones and pelvic bones. The prognosis of chondrosarcoma is
V. Monga, H. Mani, A. Hirbe, M. Milhem
semanticscholar   +1 more source

HGF and c-Met interaction promotes migration in human chondrosarcoma cells. [PDF]

PLoS ONE, 2013
Chondrosarcoma is a type of highly malignant tumor with a potent capacity for local invasion and causing distant metastasis. Chondrosarcoma shows a predilection for metastasis to the lungs.
Hsi-Kai Tsou, Hsien-Te Chen, Ya-Huey Hung, Chia-Hao Chang, Te-Mao Li, Yi-Chin Fong, Chih-Hsin Tang   +6 more
doaj   +1 more source

Chondroid Lipoma in Left Thigh –A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Chondroid lipoma is a rare variant of lipoma and often confused with chondroid tumours such as soft tissue chondroma, extraskeletal chondrosarcoma and myxoid chondrosarcoma.
Sachin Shivaji Kapse, Surekha U. Arakeri, Anita P. Javalgi   +2 more
doaj   +1 more source

Clear Cell Chondrosarcoma with Rib Cage Metastasis: Case Report

Case Reports in Oncology, 2021
Clear cell chondrosarcoma is a rare histological subtype of chondrosarcoma, usually with a relatively non-aggressive clinical course. However, infrequently they may relapse and metastasize.
Rui Caetano de Oliveira, John Reith, José Casanova   +2 more
doaj   +1 more source

Genomic Profiling Identifies Association of IDH1/IDH2 Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma

Clinical Cancer Research, 2019
Purpose: Chondrosarcomas are the second most common primary malignant bone tumors. Although histologic grade is the most important factor predicting the clinical outcome of chondrosarcoma, it is subject to interobserver variability.
G. Zhu, K. Nafa, Narasimhan P. Agaram, A. Zehir, R. Benayed, Justyna Sadowska, L. Borsu, C. Kelly, W. Tap, N. Fabbri, E. Athanasian, P. Boland, J. Healey, M. Berger, M. Ladanyi, M. Hameed   +15 more
semanticscholar   +1 more source

Is the IDH Mutation a Good Target for Chondrosarcoma Treatment?

Current Molecular Biology Reports, 2020
Chondrosarcomas are rare cancers of bone that arise from the malignant transformation of cells of chondrocytic lineage. They are known to be resistant to systemic cytotoxic chemotherapy and radiotherapy. The mainstay of management of localised disease is
E. Cojocaru, C. Wilding, Bodil Engelman, Paul H. Huang, Robin L. Jones   +4 more
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Results of a prospective phase 2 study of pazopanib in patients with surgically unresectable or metastatic chondrosarcoma

Cancer, 2019
This single‐arm, multicenter, phase 2 study evaluated the safety and antitumor activity of pazopanib in patients with unresectable or metastatic conventional chondrosarcoma.
W. Chow, P. Frankel, C. Ruel, D. Araujo, M. Milhem, S. Okuno, L. Hartner, S. Undevia, A. Staddon   +8 more
semanticscholar   +1 more source

A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression

Nature Communications, 2020
Chondrosarcomas, malignant cartilaginous neoplasms, are capable of transitioning to highly aggressive, metastatic, and treatment-refractory states, resulting in significant patient mortality.
Hyeon-Seop Kim, Yongsik Cho, Hyeon-Seop Kim, Donghyun Kang, Dong-Joo Cheon, Yi-Jun Kim, M. Chang, Kyoung Min Lee, C. Chang, Seung-Baik Kang, H. Kang, Jin-Hong Kim   +11 more
semanticscholar   +1 more source

Chondrosarcoma of the Hip [PDF]

Journal of Orthopaedic & Sports Physical Therapy, 2015
The patient was a 27-year-old woman who was being evaluated by a physical therapist 1 month following a right Achilles tendon repair. She reported the presence of a painful firm mass in her left hip that she first noticed approximately 6 months prior.
Aubrey D. Sperier, Nathan C. Hammel, Michael D. Rosenthal   +2 more
openaire   +3 more sources

Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma

Oncogene, 2019
Chondrosarcoma is the second most common malignant bone tumor. It is characterized by low vascularity and an abundant extracellular matrix, which confer these tumors resistance to chemotherapy and radiotherapy.
M. Nakagawa, F. Nakatani, Hironori Matsunaga, T. Seki, M. Endo, Y. Ogawara, Y. Machida, T. Katsumoto, Kazutsune Yamagata, Ayuna Hattori, Shuhei Fujita, Yukiko Aikawa, Takamasa Ishikawa, T. Soga, A. Kawai, H. Chuman, Nobuhiko Yokoyama, Suguru Fukushima, Kenichiro Yahiro, A. Kimura, E. Shimada, T. Hirose, T. Fujiwara, Nokitaka Setsu, Y. Matsumoto, Y. Iwamoto, Y. Nakashima, I. Kitabayashi   +27 more
semanticscholar   +1 more source