Results 81 to 90 of about 34,697 (160)

Trends in Laryngology Fellowship Training: A Survey Study of Graduates and Directors

open access: yesThe Laryngoscope, Volume 136, Issue 3, Page 1433-1443, March 2026.
A survey study of laryngology fellowship Graduates and Directors reveals overall high level of confidence in preparedness to practice in the care of most laryngologic disorders. Respondents reported less exposure to swallowing disorders in fellowship with resulting lower confidence to practice independently in this area, despite seeing a good ...
Vanessa Torrecillas   +4 more
wiley   +1 more source

Description of the immune microenvironment of chondrosarcoma and contribution to progression

open access: yesOncoImmunology, 2017
Chondrosarcoma (CHS) is a rare bone malignancy characterized by its resistance to conventional systemic and radiation therapies. Whether immunotherapy targeting immune checkpoints may be active in these tumors remains unknown.
François A. Simard   +7 more
doaj   +1 more source

Primary Meningeal Extraskeletal Osteosarcoma in a Domestic Shorthaired Cat: Case Report and Review of Comparative Pathology

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
A domestic shorthaired cat with neurological signs compatible with a forebrain lesion was investigated with magnetic resonance imaging, revealing a mass with intracranial and extracranial components. Due to the poor prognosis the cat was euthanized, and gross and histopathological examination identified an extraskeletal osteosarcoma with its origin in ...
Jacqueline Poldy   +5 more
wiley   +1 more source

BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

open access: yesBMC Cancer, 2012
Background As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their
Boeuf Stephane   +6 more
doaj   +1 more source

Real‐World Experience of Efficacy and Tolerability of Continuous Infusion Ifosfamide for Advanced Soft Tissue and Bone Sarcoma Patients: A Single Centre Retrospective Cohort

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background In the absence of randomized trials, selecting second or later‐line therapies in advanced sarcoma generally hinges on histology, patient performance status, and toxicity profile. We herein report a real‐world sarcoma referral center experience on continuous infusion Ifosfamide (ciIFO), in advanced Soft tissue sarcomas (STS) and bone
Ilaria Mascagni   +16 more
wiley   +1 more source

Is collagenase-3 (MMP-13) expression in chondrosarcoma of the jaws a true marker for tumor aggressiveness? [PDF]

open access: yes, 2008
Background Matrix metalloproteinases (MMPs) play an important role in the modeling and remodeling of the extracellular matrix in both physiologic and pathologic states and thus plays an important role in tumor progression. Human collagenase-3 (MMP-13) is
Shamaa Ali A, Zyada Manal M
core   +1 more source

What's Your Diagnosis? Large Mediastinal Mass in a Dog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz   +7 more
wiley   +1 more source

Matrix Metalloproteinase‐13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Objective Chordomas are low‐grade but invasive tumors with limited therapies. Some conventional chordomas exhibit cartilage‐like extracellular matrix (ECM). This study examined the expression and clinical significance of collagenases in chordomas.
Yumiko Oishi   +6 more
wiley   +1 more source

β5 integrin up-regulation in brain-derived neurotrophic factor promotes cell motility in human chondrosarcoma.

open access: yesPLoS ONE, 2013
Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis; it has a poor prognosis and shows a predilection for metastasis to the lungs.
Chih-Yang Lin   +6 more
doaj   +1 more source

Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone [PDF]

open access: yes, 2012
BackgroundChondrosarcoma is the second most common primary sarcoma of bone. High-grade conventional chondrosarcoma and dedifferentiated chondrosarcoma have a poor outcome.
AM Cleton-Jansen   +43 more
core   +2 more sources

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