Results 91 to 100 of about 19,107 (247)

Silencing of TRIM11 suppresses the tumorigenicity of chordoma cells through improving the activity of PHLPP1/AKT

open access: yesCancer Cell International, 2019
Background Tripartite motif-containing protein 11 (TRIM11), a member of RING family of E3 ubiquitin ligases, is identified as an oncogene in certain human tumors. However, the detailed biological function of TRIM11 in chordoma is still unclear.
Bin Wang   +6 more
doaj   +1 more source

Molecular features and vulnerabilities of recurrent chordomas

open access: yesJournal of Experimental & Clinical Cancer Research, 2021
Background Tumor recurrence is one of the major challenges in clinical management of chordoma. Despite R0-resection, approximately 50% of chordomas recur within ten years after initial surgery.
Carolin Seeling   +5 more
doaj   +1 more source

Gastrointestinal stromal tumor (GIST) of the Treitz’s angle– a very rare cause of high bowel obstruction [PDF]

open access: yes, 2016
Gastrointestinal stromal tumors (GIST) are somewhat rare gastrointestinal tumors - approximately 1% to 3% incidence, but they are the most common mesenchymal neoplasms of the gastrointestinal tract.
Georgescu, Lota Corina   +3 more
core   +3 more sources

Chordoma.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974
The history, origin, pathology, diagnosis, treatment and prognosis of chordoma involving the axial skeleton are reviewed, and the clinical histories of 3 cases of chordoma are given, noting some remarkable features, along with one case misdiagnosed as chordoma on the radiological appearance of the sacrum and treated as such, which later proved to be a ...
Fichardt, T., de Villiers, P.C.
openaire   +3 more sources

New trend in molecular diagnostics: Insights from the tumor microenvironment

open access: yesInterdisciplinary Medicine, Volume 3, Issue 6, November 2025.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan   +3 more
wiley   +1 more source

Challenging the giant: A case report on a huge sacrococcygeal chordoma and its radiological insights

open access: yesRadiology Case Reports
Sacral chordoma is a rare osseous tumor of malignant origin. Remnants of the notochord in the region of sacrum and coccyx is said to be the origin of these tumors.
Sakshi Dudhe, MBBS   +6 more
doaj   +1 more source

Stereotactic Radiosurgery Pada Benign Skull Base Tumor [PDF]

open access: yes, 2016
Total removal is difficult to be performed in skull base tumors because its location is surrounded by important structures such as nerves and blood vessels.
KODRAT, H. (HENRY)   +1 more
core  

Sacrectomía en bloque para tumores gigantes del sacro preservando las raíces de S1. Reporte de nueva técnica quirúrgica y resultado funcional [PDF]

open access: yes, 2017
Los tumores primarios de sacro son lesiones raras que se caracterizan por ser localmente agresivos, de naturaleza osteolítica y con gran potencial para recurrir a corto plazo.
Buritica, J.L   +3 more
core   +1 more source

Chordoma of the Oropharynx

open access: yesMedical Archives
Background: Chordoma is a rare malignant neoplasm that predominantly arises from the axial skeleton, but can also develop in unusual locations. However, there are also rare cases of „NOS“ chordoma involving the oropharyx and epithelial-myoepithelial carcinoma of the parotid gland in the same patient.
Ramas, Almedina   +4 more
openaire   +2 more sources

Enhanced Functional and Surgical Outcomes With 3D Printing in Orthopedic Oncology: A Comparative Meta‐Analysis Against Conventional Techniques

open access: yesJournal of Surgical Oncology, Volume 132, Issue 6, Page 1131-1142, November 2025.
ABSTRACT Introduction Three‐dimensional printing (3DP) technology has increasingly gained attention in orthopedic oncology, where complex tumor resections and reconstructions demand high precision. 3DP enables the creation of patient‐specific models and prostheses, which can improve postoperative quality of life for patients while assisting surgeons in
Peter Joseph Mounsef   +4 more
wiley   +1 more source

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