Results 71 to 80 of about 7,766 (184)
A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12
Disease Models & Mechanisms, 2014 Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither ...
Alexa Burger +7 more
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Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Objective To investigate the clinical and pathological characteristics of sellar chondroid chordoma and discuss differential diagnosis of sellar chondroid chordoma with literature review.
Xia LI +4 more
doaj
SIRT5 promote malignant advancement of chordoma by regulating the desuccinylation of c-myc
BMC CancerChordoma is a relatively rare and locally aggressive malignant tumor. Sirtuin (SIRT)5 plays pivotal roles in various tumors, but the role of SIRT5 in chordoma has not been found.
Minghui Jiang +5 more
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Acta Neuropathologica CommunicationsChordomas are clinically aggressive tumors with a high rate of disease progression despite maximal therapy. Given the limited therapeutic options available, there remains an urgent need for the development of novel therapies to improve clinical outcomes.
Shahbaz Khan +9 more
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Scientific ReportsCD3L1 (ITPRIPL1), a natural ligand of CD3ε, is implicated in tumor-immune interactions and is overexpressed in several solid tumors. However, its expression and functional significance in osteosarcoma and chordoma remain uncharacterized. This study aimed
Yuhang Wang +8 more
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