Results 1 to 10 of about 1,922,909 (309)

In vivo PET/MRI Imaging of the Chorioallantoic Membrane [PDF]

Frontiers in Physics, 2020
The Hen's Egg Test Chorioallantoic Membrane (HET-CAM) of fertilized chick eggs represents a unique model for biomedical research. With its steadily increasing use, non-invasive in ovo imaging for longitudinal direct quantification of the biodistribution ...
Gordon Winter, Andrea B. F. Koch, Jessica Löffler, Jessica Löffler, Fedor Jelezko, Mika Lindén, Hao Li, Hao Li, Alireza Abaei, Zhi Zuo, Zhi Zuo, Ambros J. Beer, Volker Rasche, Volker Rasche   +13 more
doaj   +5 more sources

QUANTIFICATION OF ANGIOGENESIS IN THE CHICKEN CHORIOALLANTOIC MEMBRANE (CAM)

Image Analysis and Stereology, 2011
The chick chorioallantoic membrane (CAM) provides a suitable in vivo model to study angiogenesis and evaluate several pro- and anti-angiogenic factors and compounds.
Silvia Blacher, Laetitia Devy, Ruslan Hlushchuk, Etienne Larger, Noel Lamandé, Peter Burri, Pierre Corvol, Valentin Djonov, Jean-Michel Foidart, Agnes Noël   +9 more
doaj   +5 more sources

The chicken chorioallantoic membrane as a low-cost, high-throughput model for cancer imaging. [PDF]

Npj Imaging, 2023
Purpose Mouse models are invaluable tools for radiotracer development and validation. They are, however, expensive, low throughput, and are constrained by animal welfare considerations.
Smith LM, Greenwood HE, Tyrrell WE, Edwards RS, de Santis V, Baark F, Firth G, Tanc M, Terry SYA, Herrmann A, Southworth R, Witney TH.   +11 more
europepmc   +2 more sources

Evolving applications of the egg: chorioallantoic membrane assay and organotypic culture of materials for bone tissue engineering

Journal of Tissue Engineering, 2020
The chick chorioallantoic membrane model has been around for over a century, applied in angiogenic, oncology, dental and xenograft research. Despite its often perceived archaic, redolent history, the chorioallantoic membrane assay offers new and exciting
Karen M Marshall, Janos M Kanczler, Richard OC Oreffo   +2 more
doaj   +2 more sources

Feasibility of the chick chorioallantoic membrane model for preclinical studies on tumor radiofrequency ablation [PDF]

European Radiology Experimental, 2023
Background We evaluated the feasibility of a chick chorioallantoic membrane (CAM) tumor model for preclinical research on tumor radiofrequency ablation (RFA). Methods Fertilized chicken eggs were incubated and divided into five cohorts: RFA for 30 s (n = 
Joel Wessendorf, Michael Scheschenja, Moritz B. Bastian, Alexander M. König, Axel Pagenstecher, Frederik Helmprobst, Malte Buchholz, Marina Tatura, Jarmila Jedelská, Andreas H. Mahnken   +9 more
doaj   +2 more sources

Chorioallantoic Membrane Models of Various Avian Species: Differences and Applications

Biology, 2021
The chorioallantoic membrane model (CAM) of an avian embryo is used as an experimental model in various fields of research, including angiogenesis research and drug testing, xenografting and cancer research, and other scientific and commercial ...
Barbora Kundeková, Mariana Máčajová, Majlinda Meta, Ivan Čavarga, Boris Bilčík   +4 more
doaj   +2 more sources

Pre-screening the intrinsic angiogenic capacity of biomaterials in an optimised chorioallantoic membrane model

Journal of Tissue Engineering, 2020
Biomaterial development for clinical applications is currently on the rise. This necessitates adequate in vitro testing, where the structure and composition of biomaterials must be specifically tailored to withstand in situ repair and regeneration ...
Nupur Kohli, Prasad Sawadkar, Sonia Ho, Vaibhav Sharma, Martyn Snow, Sean Powell, Maria A Woodruff, Lilian Hook, Elena García-Gareta   +8 more
doaj   +2 more sources

Optimisation of the Chicken Chorioallantoic Membrane Assay in Uveal Melanoma Research

Pharmaceutics, 2021
The treatment of uveal melanoma and its metastases has not evolved sufficiently over the last decades in comparison to other tumour entities, posing a great challenge in the field of ocular oncology.
Ekaterina A. Sokolenko, Utta Berchner-Pfannschmidt, Saskia C. Ting, Kurt W. Schmid, Nikolaos E. Bechrakis, Berthold Seitz, Theodora Tsimpaki, Miriam Monika Kraemer, Miltiadis Fiorentzis   +8 more
doaj   +2 more sources

Thrombin induces neoangiogenesis in the chick chorioallantoic membrane [PDF]

Journal of Thrombosis and Haemostasis, 2003
Most tumors have constitutively active tissue factor on their surface, capable of generating thrombin in the surrounding environment, and thrombosis is associated with cancer. Thrombin is known to induce a malignant phenotype by enhancing tissue adhesion and cell growth in vitro and in vivo in mice.
Simon Karpatkin, Huang Yq, Peter C. Brooks, Maresa Caunt   +3 more
openaire   +3 more sources

Establishment of a ccRCC patient-derived chick chorioallantoic membrane model for drug testing [PDF]

Frontiers in Medicine, 2022
Clear cell renal cell carcinoma (ccRCC) is an aggressive subtype of renal cell carcinoma accounting for the majority of deaths in kidney cancer patients.
Martine Charbonneau, Kelly Harper, Karine Brochu-Gaudreau, Alexis Perreault, Patrick P. McDonald, Nadia Ekindi-Ndongo, Claudio Jeldres, Claire M. Dubois   +7 more
doaj   +2 more sources