Results 101 to 110 of about 1,922,909 (309)

Hydrogel‐Based Therapies for Photoaging: Current Advances and Future Perspectives

Journal of Cosmetic Dermatology, Volume 24, Issue 6, June 2025.
ABSTRACT Background Photoaging, caused by long‐term ultraviolet (UV) exposure, leads to wrinkles, loss of skin elasticity, pigmentation disorders, and impaired barrier function due to oxidative stress, DNA damage, and collagen breakdown. Hydrogels, with their high water content (> 90%), biocompatibility, and controlled drug release capabilities, have ...
Qiong Gao, Chenghong Xu, Mingwei Tan, Yucheng Wang, YiDing Liu, Yifeng Wang, Yibin Fan, Xiaohua Tao, Wei Lu, Youming Huang, Yan Teng   +10 more
wiley   +1 more source

Sex-specific transcriptome of the chicken chorioallantoic membrane

Genomics
Dimorphism between male and female embryos has been demonstrated in many animal species, including chicken species. Likewise, extraembryonic membranes such as the chorioallantoic membrane (CAM) are likely to exhibit a sex-specific profile. Analysis of the previously published RNA-seq data of the chicken CAM sampled at two incubation times, revealed 783
Halgrain, Maeva, Bernardet, Nelly, Hennequet-Antier, Christelle, Réhault-Godbert, Sophie   +3 more
openaire   +3 more sources

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, Volume 15, Issue 5, Page 836-855, May 2025.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

Advanced Healthcare Materials, Volume 14, Issue 12, May 6, 2025.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu, Joel M. Yong, Robyn Yeh, Florence Bartlett, John M. Whitelock, Megan S. Lord   +5 more
wiley   +1 more source

Morphologic characterization of osteosarcoma growth on the chick chorioallantoic membrane

BMC Research Notes, 2010
Background The chick chorio-allantoic membrane (CAM) assay is a commonly used method for studying angiogenic or anti-angiogenic activities in vivo. The ease of access allows direct monitoring of tumour growth by biomicroscopy and the possibility to ...
Gosheger Georg, Gebert Carsten, Agelopoulos Konstantin, Kersting Christian, Neumann Anna, Balke Maurice, Buerger Horst, Hagedorn Martin   +7 more
doaj   +1 more source

* The Chorioallantoic Membrane Assay for Biomaterial Testing in Tissue Engineering: A Short-Term In Vivo Preclinical Model.

Tissue Engineering. Part C, Methods, 2017
The fields of regenerative medicine and tissue engineering offer significant promise to address the urgent unmet need for therapeutic strategies in a number of debilitating conditions, diseases, and tissue needs of an aging population.
I. Moreno-Jiménez, J. Kanczler, G. Hulsart-Billstrom, S. Inglis, R. Oreffo   +4 more
semanticscholar   +1 more source

Natural products targeting tumour angiogenesis

British Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu, Lara Johanna Friedrich, Thomas Efferth   +2 more
wiley   +1 more source

The Effects of Total Extract Ocimumbasilicumon VEGF Gene Expression Changes in Chick Embryo Chorioallantoic Membrane Angiogenesis

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2017
Introduction: Angiogenesis is one of the most important biological processes that any disruption of it can cause diseases. The main point of the molecular guidance in this process is the vascular endothelial growth factor (VEGF) that acts through its ...
Fateme Niazi, Khadije Shahrokh abadi, Maryam Tehranipour   +2 more
doaj  

Graphene Oxide in a Composite with Silver Nanoparticles Reduces the Fibroblast and Endothelial Cell Cytotoxicity of an Antibacterial Nanoplatform

Nanoscale Research Letters, 2019
Antibacterial surfaces coated with nanomaterials, including silver nanoparticles, are considered effective alternative antimicrobial agents that can be used instead of antibiotics and chemical agents.
Mateusz Wierzbicki, Sławomir Jaworski, Ewa Sawosz, Anna Jung, Grzegorz Gielerak, Henryk Jaremek, Witold Łojkowski, Bartosz Woźniak, Leszek Stobiński, Artur Małolepszy, André Chwalibog   +10 more
doaj   +1 more source

Standardization of A375 human melanoma models on chicken embryo chorioallantoic membrane and Balb/c nude mice

Oncology Report, 2017
Cutaneous melanoma is a metastatic disease characterized by high resistance to treatment, the incidence of which has alarmingly increased worldwide over the past years.
Ș. Avram, D. Coricovac, I. Pavel, I. Pinzaru, Roxana M. Ghiulai, F. Baderca, Codruța Șoica, D. Muntean, D. Branisteanu, D. Spandidos, A. Tsatsakis, C. Dehelean   +11 more
semanticscholar   +1 more source