Results 61 to 70 of about 4,684 (170)

Pectate lyase is a factor in the adaptability for Heterodera glycines infecting tobacco

Journal of Integrative Agriculture, 2019
The soybean cyst nematode, Heterodeara glycines, is a serious pathogen of soybean, and reported to be the host of a wide range of Fabaceae. In the present study, the host specificity and reproductivity of two populations of H.
Zhong-ling TIAN, Hong-li SHI, Munawar Maria, Jing-wu ZHENG   +3 more
doaj   +1 more source

Beet Chlorosis Virus Infection Mitigates Aphid‐Induced Plant Defences and Improves Plant Acceptability to Aphid Vectors

Molecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT Plant viruses often alter host traits in ways that affect interactions with herbivores, potentially facilitating their own acquisition and transmission by insect vectors. However, little is known about the molecular mechanisms underlying this phenomenon.
Thomas Armand, Sylvaine Boissinot, Alessandra Maia‐Grondard, Philippe Hugueney, Véronique Brault, Quentin Chesnais   +5 more
wiley   +1 more source

Metabolic engineering of Synechocystis sp. PCC 6803 for the improved production of phenylpropanoids

Microbial Cell Factories
Background Phenylpropanoids are a large group of plant secondary metabolites with various biological functions, derived from aromatic amino acids. Cyanobacteria are promising host organisms for sustainable production of plant phenylpropanoids.
Kateryna Kukil, Pia Lindberg
doaj   +1 more source

Directed evolution of a model primordial enzyme provides insights into the development of the genetic code.

PLoS Genetics, 2013
The contemporary proteinogenic repertoire contains 20 amino acids with diverse functional groups and side chain geometries. Primordial proteins, in contrast, were presumably constructed from a subset of these building blocks.
Manuel M Müller, Jane R Allison, Narupat Hongdilokkul, Laurent Gaillon, Peter Kast, Wilfred F van Gunsteren, Philippe Marlière, Donald Hilvert   +7 more
doaj   +1 more source

A chorismate mutase from Radopholus similis plays an essential role in pathogenicity

Journal of Integrative Agriculture
In the process of infecting plants, plant parasitic nematodes release a series of proteins that play an essential role in the successful infection and pathogenesis of plant cells and tissues through stylets or body walls.
Sihua Yang, Junyi Li, Shuai Yang, Shiqiao Tang, Huizhong Wang, Chunling Xu, Hui Xie   +6 more
doaj   +1 more source

Mechanistic studies of an antibody with chorismate mutase activity

Bioorganic & Medicinal Chemistry Letters, 1994
Abstract Antibody 1F7 catalyzes the rearrangement of chorismate to prephenate. Its kinetic parameters are unaffected by changes in pH and display no solvent isotope effect or effects from addition of various cationic salts. These results are consistent with high-resolution structural information of 1F7 bound to a transition state analog.
Jumi A. Shin, Donald Hilvert
openaire   +1 more source

Transition-state analogue inhibitors of chorismate mutase

Tetrahedron, 1990
Abstract The synthesis of seven bi- and tricyclic chorismate analogues 9 - 15 and their biological evaluation as mutase inhibitors is described. A tandem Cope rearrangement/Diels-Alder cycloaddition strategy was employed to prepare tricyclo[3.3.1.02,7]non-3-enes functionalized with carboxylic and/or phosphonic acid groups.
Trafford Clarke, Jon D. Stewart, Bruce Ganem   +2 more
openaire   +1 more source

A Puccinia striiformis f. sp. tritici Effector with DPBB Domain Suppresses Wheat Defense

Plants
Wheat (Triticum aestivum L.) is a primary crop globally. Among the numerous pathogens affecting wheat production, Puccinia striiformis f. sp. tritici (Pst) is a significant biotic stress agent and poses a major threat to world food security by causing ...
Raheel Asghar, Yu Cheng, Nan Wu, Mahinur S. Akkaya   +3 more
doaj   +1 more source

A secreted form of chorismate mutase (Rv1885c) in Mycobacterium bovis BCG contributes to pathogenesis by inhibiting mitochondria-mediated apoptotic cell death of macrophages. [PDF]

J Biomed Sci, 2023
Lee MH, Kim HL, Seo H, Jung S, Kim BJ.
europepmc   +1 more source

Early preclinical development of Mycobacterium tuberculosis amino acid biosynthesis pathway inhibitor DRILS-1398 as a potential anti-TB drug

iScience
Summary: The search for new anti-tubercular agents is vital for the fight against Mycobacterium tuberculosis, particularly given the rise of drug-resistant strains.
Deepesh Biswas, Rebecca Kristina Edwin, K. Shiva Kumar, Anwar Alam, Dhiraj Kumar, Sandipan Chakraborty, Gopalakrishnan Bulusu, Farhan Jalees Ahmad, Gautham G. Shenoy, Lakshyaveer Singh, Mansi Agarwal, Fouzia Siraj, Srinivas Oruganti, Parimal Misra, Nasreen Zafar Ehtesham, Manojit Pal, Seyed Ehtesham Hasnain   +16 more
doaj   +1 more source