Results 1 to 10 of about 167,748 (392)

Choroid plexus epithelium and its role in neurological diseases

Frontiers in Molecular Neuroscience, 2022
Choroid plexus epithelial cells can secrete cerebrospinal fluid into the ventricles, serving as the major structural basis of the selective barrier between the neurological system and blood in the brain.
Ruizhen Liu, Ruizhen Liu, Ruizhen Liu, Zhiping Zhang, Zhiping Zhang, Zhiping Zhang, Yibing Chen, Yibing Chen, Yibing Chen, Junbo Liao, Junbo Liao, Junbo Liao, Yuchang Wang, Yuchang Wang, Yuchang Wang, Jingping Liu, Jingping Liu, Jingping Liu, Zhixiong Lin, Gelei Xiao, Gelei Xiao, Gelei Xiao   +21 more
doaj   +2 more sources

Klotho controls the brain-immune system interface in the choroid plexus. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2018
Located within the brain's ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood.
Ho, Kaitlyn, Kim, Daniel, Larsson, Tobias E, Mucke, Lennart, Stein, Liana R, Yu, Gui-Qiu, Zhan, Lihong, Zhu, Lei   +7 more
core   +2 more sources

Choroidal vascularity index as a measure of vascular status of the choroid: Measurements in healthy eyes from a population-based study

Scientific Reports, 2016
The vascularity of the choroid has been implicated in the pathogenesis of various eye diseases. To date, no established quantifiable parameters to estimate vascular status of the choroid exists.
Rupesh Agrawal Fcrs, Chui Ming Gemmy Cheung, Ching-Yu Cheng   +2 more
exaly   +2 more sources

Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance The retinal pigment epithelium and the choroid are complex tissues whose dysfunction can lead to irreversible visual loss. In this study, single-cell RNA sequencing of both of these tissues was performed to characterize gene expression ...
Andrew P Voigt, Kelly Mulfaul, Nathaniel K Mullin   +2 more
exaly   +2 more sources

Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling

Fluids and Barriers of the CNS, 2020
Background The choroid plexus is a major contributor to the generation of cerebrospinal fluid (CSF) and the maintenance of its electrolyte and metabolite balance.
Li Zhao, Manuel Taso, Weiying Dai, Daniel Z. Press, David C. Alsop   +4 more
doaj   +2 more sources

The choroid plexus is an important circadian clock component

Nature Communications, 2018
Mammalian circadian clocks have a hierarchical organization, governed by the suprachiasmatic nucleus (SCN) in the hypothalamus. The brain itself contains multiple loci that maintain autonomous circadian rhythmicity, but the contribution of the non-SCN ...
Jihwan Myung, Christoph Schmal, Sungho Hong   +2 more
exaly   +2 more sources

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

EMBO Molecular Medicine, 2016
Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood–brain communication. Systemic inflammation induced an increase in EVs and associated pro‐inflammatory miRNAs, including miR ...
Sriram Balusu, Riet De Rycke, Koen Raemdonck   +2 more
exaly   +2 more sources

Dysregulation of brain and choroid plexus cell types in severe COVID-19

Nature, 2021
Andrew C Yang, Fabian Kern, Tobias Fehlmann   +2 more
exaly   +2 more sources

The multifunctional choroid

Progress in Retinal and Eye Research, 2010
Debora L Nickla
exaly   +2 more sources

Development and functions of the choroid plexus–cerebrospinal fluid system

Nature Reviews Neuroscience, 2015
Edwin S Monuki, Maria K Lehtinen
exaly   +2 more sources