Results 11 to 20 of about 165,368 (343)
Choroid plexus epithelium and its role in neurological diseases
Frontiers in Molecular Neuroscience, 2022 Choroid plexus epithelial cells can secrete cerebrospinal fluid into the ventricles, serving as the major structural basis of the selective barrier between the neurological system and blood in the brain.
Ruizhen Liu +21 more
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Klotho controls the brain-immune system interface in the choroid plexus. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 Located within the brain's ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood.
Ho, Kaitlyn +7 more
core +2 more sources
Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling
Fluids and Barriers of the CNS, 2020 Background The choroid plexus is a major contributor to the generation of cerebrospinal fluid (CSF) and the maintenance of its electrolyte and metabolite balance.
Li Zhao +4 more
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IMI—The Dynamic Choroid: New Insights, Challenges, and Potential Significance for Human Myopia
Investigative Ophthalmology and Visual Science, 2023 The choroid is the richly vascular layer of the eye located between the sclera and Bruch's membrane. Early studies in animals, as well as more recent studies in humans, have demonstrated that the choroid is a dynamic, multifunctional structure, with its ...
Lisa A. Ostrin +8 more
semanticscholar +1 more source
Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited
Fluids and Barriers of the CNS, 2022 Cerebrospinal fluid (CSF) envelops the brain and fills the central ventricles. This fluid is continuously replenished by net fluid extraction from the vasculature by the secretory action of the choroid plexus epithelium residing in each of the four ...
N. MacAulay, R. Keep, T. Zeuthen
semanticscholar +1 more source
Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder
Neurology, 2022 The choroid plexus has been shown to play a crucial role in CNS inflammation. Previous studies found larger choroid plexus in multiple sclerosis (MS) compared with healthy controls.
J. Müller +34 more
semanticscholar +1 more source
The choroid plexus and its role in the pathogenesis of neurological infections
Fluids and Barriers of the CNS, 2022 The choroid plexus is situated at an anatomically and functionally important interface within the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the periphery from the central nervous system.
Derick Thompson, C. Brissette, J. Watt
semanticscholar +1 more source
Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Neuroinflammation is a hallmark of multiple sclerosis and is linked to neurodegeneration. This study provides pathophysiological insights into the cross-dependency between neuroinflammation and choroid plexus characteristics in both mice and
V. Fleischer +20 more
semanticscholar +1 more source
Acta ophthalmologica, 2021 Myopia is the most common type of refractive errors characterized by excessive elongation of the ocular globe. With the increasing prevalence of myopia, improved knowledge of factors involved in myopia development is of particular importance.
Yilin Liu +4 more
semanticscholar +1 more source
Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate
Nature Communications, 2022 The choroid plexus secretes cerebrospinal fluid and is critical for the development and function of the brain. In the telencephalon, the choroid plexus epithelium arises from the Wnt- expressing cortical hem.
Arpan Parichha +13 more
semanticscholar +1 more source