Results 31 to 40 of about 77,043 (265)

Unmasking of molecular players: proteomic profiling of vitreous humor in pathologic myopia

BMC Ophthalmology
Background This study aimed to identify the differentially expressed proteins in the vitreous humor (VH) of eyes with and without pathologic myopia (PM), providing insights into the molecular pathogenesis.
Yue Wen, Chi Ren, Li Zhu, Lvzhen Huang, Huijun Qi, Wenzhen Yu, Kai Wang, Mingwei Zhao, Qiong Xu   +8 more
doaj   +1 more source

Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells

Journal of Ophthalmology, 2018
Purpose. Secondary open-angle glaucoma may develop as a postoperative complication of early childhood cataract surgery. Its mechanism is poorly understood.
Hui Xu, Li Zhu, Yu Wang, Yongzhen Bao
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Diurnal changes of retinal microvascular circulation and RNFL thickness measured by optical coherence tomography angiography in patients with obstructive sleep apnea–hypopnea

Frontiers in Endocrinology, 2022
PurposeTo evaluate capillaries perfusion and retinal nerve fiber layer (RNFL) thickness diurnal changes of macular/optic disc regions among participants with or without obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence ...
Yi Cai, Wen-Bo Liu, Miao Zhou, Yu-Tong Jin, Guo-Sheng Sun, Long Zhao, Fang Han, Jin-Feng Qu, Xuan Shi, Ming-Wei Zhao   +9 more
doaj   +1 more source

Topographic distribution features of the choroidal and retinal nerve fiber layer thickness in Chinese school-aged children [PDF]

International Journal of Ophthalmology, 2020
AIM: To explore the topographic distribution features of choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT), and determine the relationship between CT and ocular parameters in school-aged children.
Wei-Qin Liu, Dan-Dan Wang, Xiao-Xia Yang, Yan-Yan Pan, Xue Song, Yu-Shan Hou, Chen-Xiao Wang   +6 more
doaj   +1 more source

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

Arthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan, Catherine M. Guly, Gabriele Simonini, Stuart Y. Keller, Priyanka Sen, Thorsten Holzkaemper, Joana Araújo, Pierre Quartier   +7 more
wiley   +1 more source

Direct observation and measurement of circumlental space and its relation to anterior chamber angle characteristics in iridotomized phakic eyes with primary angle closure disease

Scientific Reports
Primary angle closure disease (PACD) is a major cause of blindness worldwide. It has a high prevalence in East Asia, especially in China, which leads to a higher incidence of blindness than open-angle glaucoma.
Zhiqiao Liang, Kangyi Yang, Kun Lv, Yao Ma, Xuanzhu Chen, Zeqin Ren, Yong Liang, Xianru Hou, Huijuan Wu   +8 more
doaj   +1 more source

Comparative morphological analysis of the zonular apparatus in porcine, feline, and canine species

Frontiers in Medicine
PurposeTo characterize and compare the morphology of the zonular apparatus in pigs, cats, and dogs to identify the optimal animal model for studying zonular pathophysiology in angle-closure mechanisms.MethodsPorcine (n = 15), feline (n = 8), and canine ...
Ye Lu, Ye Lu, Kuankuan Wu, Kuankuan Wu, Zhiqiao Liang, Zhiqiao Liang, Kun Lv, Kun Lv, Zeyuan Wang, Zeyuan Wang, Fengrui Yang, Fengrui Yang, Yitong Hu, Yitong Hu, Huijuan Wu, Huijuan Wu   +15 more
doaj   +1 more source

Changes in the Foveal Outer Nuclear Layer of Central Serous Chorioretinopathy Patients Over the Disease Course and Their Response to Photodynamic Therapy

Frontiers in Medicine, 2022
Objective:To investigate the association between foveal outer nuclear layer (ONL) thickness and the natural course of central serous chorioretinopathy (CSC), as well as the thickness change after photodynamic therapy (PDT), exploring the PDT timing for ...
Kaixin Deng, Kaixin Deng, Kaixin Deng, Kaixin Deng, Yufei Gui, Yufei Gui, Yufei Gui, Yufei Gui, Yi Cai, Yi Cai, Yi Cai, Yi Cai, Zhiqiao Liang, Zhiqiao Liang, Zhiqiao Liang, Zhiqiao Liang, Xuan Shi, Xuan Shi, Xuan Shi, Xuan Shi, Yaoyao Sun, Yaoyao Sun, Yaoyao Sun, Yaoyao Sun, Mingwei Zhao, Mingwei Zhao, Mingwei Zhao, Mingwei Zhao   +27 more
doaj   +1 more source