Background To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence tomography angiography (OCTA). Methods There were 60 eyes of 31 volunteers enrolled in this
Mengyang Li+5 more
doaj +1 more source
BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity
BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity. Abstract Purpose To report novel BEST1 variants in six Chinese families with bestrophinopathies of two different inheritance modes and analyze the intrafamilial phenotypic diversity.
Shangying Yang+8 more
wiley +1 more source
Functional and Genetic Analysis of Choroid Plexus Development in Zebrafish
The choroid plexus, an epithelial-based structure localized in the brain ventricle, is the major component of the blood-cerebrospinal fluid barrier. The choroid plexus produces the cerebrospinal fluid and regulates the components of the cerebrospinal ...
Hannah Elizabeth Henson+5 more
doaj +1 more source
Automated segmentation of choroidal layers from 3-dimensional macular optical coherence tomography scans [PDF]
Background: Changes in choroidal thickness are associated with various ocular diseases and the choroid can be imaged using spectral-domain optical coherence tomography (SDOCT) and enhanced depth imaging OCT (EDIOCT). New Method: Eighty macular SDOCT volumes from 80 patients were obtained using the Zeiss Cirrus machine.
arxiv
The present pilot study examined the ability of 18F‐PI‐2620 tau PET tracer to distinguish between healthy control and Alzheimer's disease, as well as correlations with plasma p‐tau181 and cognitive test results. Though the sample size was small, seven for each group, its SUVR in the target brain regions showed distinct differences between them and high
Shogyoku Bun+14 more
wiley +1 more source
Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells
Purpose. Secondary open-angle glaucoma may develop as a postoperative complication of early childhood cataract surgery. Its mechanism is poorly understood.
Hui Xu, Li Zhu, Yu Wang, Yongzhen Bao
doaj +1 more source
Analysis of retinal and choroidal images measured by laser Doppler holography [PDF]
Laser Doppler holography (LDH) is a full-field imaging technique that was recently used in the human eye to reveal blood flow contrasts in the retinal and choroidal vasculature non-invasively, and with high temporal resolution. We here demonstrate that the ability of LDH to perform quantitative flow measurements with high temporal resolution enables ...
arxiv +1 more source
Evaluation of an automated choroid segmentation algorithm in a longitudinal kidney donor and recipient cohort [PDF]
Purpose: To evaluate the performance of an automated choroid segmentation algorithm in optical coherence tomography (OCT) data using a longitudinal kidney donor and recipient cohort. Methods: We assessed 22 donors and 23 patients requiring renal transplantation over up to 1 year post-transplant.
arxiv
Fetal cerebral ventriculomegaly: What do we tell the prospective parents?
Abstract Fetal cerebral ventriculomegaly is a relatively common finding, observed during approximately 1% of obstetric ultrasounds. In the second and third trimester, mild (≥10 mm) and severe ventriculomegaly (≥15 mm) are defined according to the measurement of distal lateral ventricles that is included in the routine sonographic examination of central
Veronica Giorgione+4 more
wiley +1 more source
Unmasking of molecular players: proteomic profiling of vitreous humor in pathologic myopia
Background This study aimed to identify the differentially expressed proteins in the vitreous humor (VH) of eyes with and without pathologic myopia (PM), providing insights into the molecular pathogenesis.
Yue Wen+8 more
doaj +1 more source