Results 61 to 70 of about 78,813 (321)

An open-source deep learning algorithm for efficient and fully-automatic analysis of the choroid in optical coherence tomography [PDF]

arXiv, 2023
Purpose: To develop an open-source, fully-automatic deep learning algorithm, DeepGPET, for choroid region segmentation in optical coherence tomography (OCT) data. Methods: We used a dataset of 715 OCT B-scans (82 subjects, 115 eyes) from 3 clinical studies related to systemic disease.
arxiv  

THE ETIOLOGY OF CHOROIDITIS. [PDF]

JAMA: The Journal of the American Medical Association, 1905
The following observations regarding the causal relations of choroiditis with rubeola are the results of observations of numerous cases of this disease which have come under my observation. It has always seemed to the writer that the pathology of choroiditis has not been so definitely established or defined as to enable the practitioner to feel that he
openaire   +3 more sources

Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic ...
Ahmed Y. Azzam, Muhammed Amir Essibayi, Dhrumil Vaishnav, Mohammed A. Azab, Mahmoud M. Morsy, Osman Elamin, Adam Elswedy, Oday Atallah, Hana J. Abukhadijah, Adam A. Dmytriw, Amanda Baker, Deepak Khatri, Neil Haranhalli, David J. Altschul   +13 more
wiley   +1 more source

Survival rates and outcomes of pregnancies with prenatal diagnosis of trisomy 18: A 16‐year experience from a public hospital in South Africa

Prenatal Diagnosis, Volume 42, Issue 13, Page 1643-1649, December 2022., 2022
Abstract Objective Many studies, largely from high‐income countries (HIC), have reported outcomes in babies with trisomy 18 (T18), with a paucity of data from Africa. Knowledge of outcomes is important in counselling women prenatally diagnosed with T18.
Chantal Stewart, Atta Owusu‐Bempah, Alison Boutall, Sonia Barr, Tina‐Marié Wessels, Karen Fieggen   +5 more
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Transcriptomic Profiling Unveils EDN3+ Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis

Advanced Science, EarlyView.
Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformations, leading to seizures and stroke. Analysis of 119 446 brain cells from SWS patients uncovered distinct cell heterogeneity and identified an EDN3⁺ meningeal fibroblast cluster, with WNT5A emerging as a potential key driver of SWS progression and a promising therapeutic ...
Daosheng Ai, Tianyue Ming, Xiaoli Li, Shu Wang, Zhanying Bi, Jinyi Zuo, Zizhang Cheng, Weijin Sun, Mingguo Xie, Fengzhi Li, Xiongfei Wang, Xueling Qi, Guoming Luan, Woo‐ping Ge, Yuguang Guan   +14 more
wiley   +1 more source

Direct observation and measurement of circumlental space and its relation to anterior chamber angle characteristics in iridotomized phakic eyes with primary angle closure disease

Scientific Reports
Primary angle closure disease (PACD) is a major cause of blindness worldwide. It has a high prevalence in East Asia, especially in China, which leads to a higher incidence of blindness than open-angle glaucoma.
Zhiqiao Liang, Kangyi Yang, Kun Lv, Yao Ma, Xuanzhu Chen, Zeqin Ren, Yong Liang, Xianru Hou, Huijuan Wu   +8 more
doaj   +1 more source

Automated segmentation and extraction of posterior eye segment using OCT scans [PDF]

arXiv, 2021
This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT) scans. The proposed method works in two phases.
arxiv  

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Short-Term Results of Switch from Conbercept to Bevacizumab or Ranibizumab in Eyes with Persistent Neovascular Age-Related Macular Degeneration

Journal of Ophthalmology, 2020
Purpose. To study the short-term anatomical and functional outcomes in patients with neovascular age-related macular degeneration (nAMD) who were previously treated with conbercept and switched to ranibizumab or bevacizumab due to persistent activity ...
Zongyi Wang, Mengyang Li, Yuou Yao, Jie Hu, Jiyang Tang, Ran Tang, Zhenyu Piao, Jinfeng Qu   +7 more
doaj   +1 more source