Associations of Cone Density and Choroidal Thickness with Age: A Cross-Sectional Study. [PDF]
Lin J +12 more
europepmc +1 more source
ABSTRACT Background To determine whether axial length‐related magnification correction in optical coherence tomography angiography (OCTA) improves machine learning classification of high myopia and resolves inconsistencies in the values and discriminatory power of OCTA microvascular metrics.
Danuta M. Sampson +9 more
wiley +1 more source
Disease-specific patterns of glymphatic-related dysfunction between multiple sclerosis and neuromyelitis optica spectrum disorder. [PDF]
Chen X +9 more
europepmc +1 more source
Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source
Non-Infectious Choroiditis Subdivided into Its Diverse Pathophysiological Sub-Groups Is the Best-Known and Most Appropriate Nomenclature to Date for the Reclassification and Diagnosis of Former White Dot Entities. [PDF]
Herbort CP +15 more
europepmc +1 more source
Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon +12 more
wiley +1 more source
Ascorbic acid transport via choroid plexus measured with 6-deoxy-6-[<sup>18</sup>F]fluoro-L-ascorbic acid PET. [PDF]
Zhang Y +11 more
europepmc +1 more source
Using a novel capillary Western blot, we quantified Pan‐ApoE and ApoE4 in 34 paired CSF and serum samples. CSF/serum quotient analysis showed that less than 1.5% of CSF ApoE can be explained by passive diffusion across the blood‐CSF barrier, indicating that more than 98.5% originates from the central nervous system through local synthesis and active ...
Eric Kortmann +4 more
wiley +1 more source
A Novel Ocular Fibrosis Signature for AMD Using the Two-Stage Laser-Induced Subretinal Fibrosis Mouse Model. [PDF]
Hughes D +8 more
europepmc +1 more source
Preclinical Models of Uveal Melanoma: Strengths, Limitations, and Translational Utility
This review summarizes experimental models of uveal melanoma, including 2D cell cultures, 3D spheroids and organoids, animal models, and emerging platforms. These models facilitate investigations of molecular mechanisms, metastasis, diagnostics, and therapeutics, but differ in their ability to recapitulate genetic fidelity, tumor microenvironment, and ...
Yunxi Chen +2 more
wiley +1 more source

