Results 211 to 220 of about 49,505 (301)

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Gyrate Atrophy of the Choroid and Retina Diagnosed in Adulthood With a Homozygous <i>OAT</i> Variant: A Case Report Highlighting the Need for Long-Term Care. [PDF]

Case Rep Ophthalmol Med
Taniai H, Mizobuchi K, Hara T, Hayashi T, Nakano T.   +4 more
europepmc   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

Association between choroidal thickness and primary open angle glaucoma in highly myopic eyes. [PDF]

Int J Ophthalmol
Jin PY, Tang M, Zhou MW, Fan Y, Ling YY, Zhu JF, Zou HD, He JN, Xue WW.   +8 more
europepmc   +1 more source

Beyond the Known and Established Neurodegenerative Effects: Roles of APOE Across a Wide Spectrum of Pathophysiological Condition

MedComm, Volume 7, Issue 6, June 2026.
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina, Samantha Maurotti, Alberto Castagna, Tiziana Montalcini, Arturo Pujia, Luca Tirinato   +5 more
wiley   +1 more source

Altered glymphatic function in nasopharyngeal carcinoma following radiotherapy: novel insights from choroid plexus volume and free-water fraction analyses. [PDF]

Front Neurosci
Deng L, Peng J, Zhou K, Fan K, Xia Y, Zhang S, Li L, Gao JM, Jiang N, Zhang Y.   +9 more
europepmc   +1 more source

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Choroid plexus cyst burden is associated with glymphatic dysfunction and cognitive impairment in hepatic encephalopathy. [PDF]

Hepatol Commun
Chen L, Zhang Z, Fang J, Cai L, Zeng Z, Liu Y, Zheng J, Fu L, Hong C, Chen Y, Wang X, Li D.   +11 more
europepmc   +1 more source

Rapid Tissue‐CSF Water Exchange in the Human Brain Revealed by Magnetization Transfer Indirect Spin Labeling

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3270-3283, June 2026.
ABSTRACT Purpose To apply the Magnetization Transfer Indirect Spin Labeling (MISL) MRI technique for quantifying tissue‐CSF water exchange in the human brain, and to investigate its utility in (1) evaluating tissue‐CSF water exchange within perivascular spaces (PVS), and (2) characterizing altered water exchange dynamics in pathologic conditions ...
Yihan Wu, Kexin Wang, Licheng Ju, Anna Li, Qin Qin, Feng Xu, Doris D. M. Lin, Lawrence Kleinberg, Jiadi Xu   +8 more
wiley   +1 more source

Subfoveal Choroidal Thickness in Clinically Significant Pseudophakic Cystoid Macular Edema: An Interocular Comparison with Contralateral Pseudophakic Eyes. [PDF]

Clin Ophthalmol
Demir K, Çelik E.
europepmc   +1 more source