Results 91 to 100 of about 13,661 (222)

A rare trifocal presentation of a choroid plexus papilloma: Case report and review of the literature

open access: yesBrain and Spine
Introduction: CPP's present as slow-growing intraventricular neoplasms arising from epithelium of choroid plexus. They account for approximately 0.5–4% of intracranial neoplasms in adults and children, respectively. A trifocal presentation is exceedingly
Senne Broekx, Mania De Praeter
doaj   +1 more source

The Clinical Characteristics and Treatment of Patients With Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP‐A): A Retrospective Study of 29 Patients

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
A retrospective analysis of clinical features, treatment, and outcome of 29 patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A). Cerebrospinal fluid (CSF) pressure, CSF nucleated cell count, CSF protein levels, CSF chloride, serum thyroid dysfunction, and abnormal blood cytokine levels correlated with disease severity but ...
Xuewei Yang   +6 more
wiley   +1 more source

PAPILLARY GLIONEURONAL TUMOR OF THE POSTERIOR FOSSA

open access: yesRevista Ciencias Biomédicas, 2015
Introduction: the papillary glioneuronal tumor (PGT) is an uncommon disease and it has recent categorization. It has probable origin in the pluripotent stem cells of the subependymal zone that is located mainly around the temporal horns of the lateral
Tuñón-Pitalúa Martha Cecilia   +5 more
doaj  

Beyond Treatment: The Strategy of Nonintervention in Choroidal Hemangioma

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT The circumscribed choroidal hemangioma (CCH) is a benign congenital eye tumor whose etiology is not clear. A 41‐year‐old female patient came with a 2‐year history of slowly progressive deteriorating vision in her right eye. In the left eye, the best‐corrected visual acuity (BCVA) was 6/6, and counting fingers at 1 m in the right eye.
Humdan Khan   +8 more
wiley   +1 more source

FABP4‐mediated lipid droplet accumulation drives epithelial–mesenchymal transition and aggravates alveolar epithelial barrier disruption

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
LIRI induces FABP4 secretion, driving lipid droplets accumulation in alveolar epithelial cells. FABP4 activates p38 MAPK/ULK1 signalling to inhibit lipophagy and promote lipid storage. Lipid droplets trigger epithelial–mesenchymal transition and disrupt alveolar barrier. Elevated FABP4 predicts ARDS in cardiopulmonary bypass patients.
Zihao Shen   +11 more
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

Clinical Features and Treatment Strategies of Li‐Fraumeni Syndrome Patients With Inherited TP53 Mutations

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
LFS with TP53 disease‐causing mutations may be potential beneficiaries of immune checkpoint inhibitors and targeted therapies. Therefore, NGS and PD‐L1 testing should be performed in all LFS patients. ABSTRACT Background Li‐Fraumeni syndrome is a rare autosomal dominant disorder caused by a pathogenic mutation of the tumor suppressor gene TP53.
Keyu Chen   +6 more
wiley   +1 more source

Pediatric brain tumor classification using digital pathology and deep learning: Evaluation of SOTA methods on a multi‐center Swedish cohort

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Deep learning‐based feature extractors pretrained on histopathology images can classify pediatric brain tumors when applied to a multi‐center Swedish dataset. Abstract Brain tumors are the most common solid tumors in children and young adults, but the scarcity of large histopathology datasets has limited the application of computational pathology in ...
Iulian Emil Tampu   +9 more
wiley   +1 more source

A Benign Giant Fibroblastic Intraventricular Meningioma: A Rare Case Report with Review of Literature

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Intraventricular meningiomas are uncommon neoplasms and account for only 0.5 to 3%. They are seen mostly in the age group of 12 to 14 years. They arise from the arachnoid cap cells located in the choroid plexus.
Shirish S. Chandanwale   +2 more
doaj   +1 more source

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