Results 1 to 10 of about 166,293 (242)

Choroid plexus epithelium and its role in neurological diseases

Frontiers in Molecular Neuroscience, 2022
Choroid plexus epithelial cells can secrete cerebrospinal fluid into the ventricles, serving as the major structural basis of the selective barrier between the neurological system and blood in the brain.
Ruizhen Liu, Ruizhen Liu, Ruizhen Liu, Zhiping Zhang, Zhiping Zhang, Zhiping Zhang, Yibing Chen, Yibing Chen, Yibing Chen, Junbo Liao, Junbo Liao, Junbo Liao, Yuchang Wang, Yuchang Wang, Yuchang Wang, Jingping Liu, Jingping Liu, Jingping Liu, Zhixiong Lin, Gelei Xiao, Gelei Xiao, Gelei Xiao   +21 more
doaj   +2 more sources

The choroid plexus and its role in the pathogenesis of neurological infections

Fluids and Barriers of the CNS, 2022
The choroid plexus is situated at an anatomically and functionally important interface within the ventricles of the brain, forming the blood-cerebrospinal fluid barrier that separates the periphery from the central nervous system.
Derick Thompson, Catherine A. Brissette, John A. Watt   +2 more
doaj   +2 more sources

Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling

Fluids and Barriers of the CNS, 2020
Background The choroid plexus is a major contributor to the generation of cerebrospinal fluid (CSF) and the maintenance of its electrolyte and metabolite balance.
Li Zhao, Manuel Taso, Weiying Dai, Daniel Z. Press, David C. Alsop   +4 more
doaj   +2 more sources

Evidence for reduced choroid plexus volume in the aged brain [PDF]

Fluids and Barriers of the CNS
Background The choroid plexus plays an important role in brain homeostasis, including the active secretion of cerebrospinal fluid. Its function and structure have been reported to be affected by normal ageing. However, existing measures of choroid plexus
R. Youh, C. Perera, C. Katsiva, I. F. Harrison, M. F. Lythgoe, D. K. Wright, S. Nizari, Jack A. Wells   +7 more
doaj   +2 more sources

Klotho controls the brain-immune system interface in the choroid plexus. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2018
Located within the brain's ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood.
Ho, Kaitlyn, Kim, Daniel, Larsson, Tobias E, Mucke, Lennart, Stein, Liana R, Yu, Gui-Qiu, Zhan, Lihong, Zhu, Lei   +7 more
core   +2 more sources

Choroid plexus volume in brain disorders: a systematic review [PDF]

Fluids and Barriers of the CNS
Background The choroid plexus is a highly vascularized structure located in the lateral, third, and fourth ventricles of the brain. Recent studies suggest that volumetric changes in choroid plexus volume are associated with progression in various brain ...
Derya Tireli, Jeppe Romme Christensen, Tina Nørgaard Munch, Nanna MacAulay, Henrik Bo Wiberg Larsson, Jonathan Frederik Carlsen, Stig Praestekjaer Cramer   +6 more
doaj   +2 more sources

Dysregulation of brain and choroid plexus cell types in severe COVID-19

Nature, 2021
Andrew C Yang, Fabian Kern, Tobias Fehlmann   +2 more
exaly   +2 more sources

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles [PDF]

EMBO Molecular Medicine, 2016
Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood-brain communication. Systemic inflammation induced an increase in EVs and associated pro-inflammatory miRNAs, including miR ...
An Hendrix, Beutler B, Claude Libert, Delphine Demeestere, Elien Van Wonterghem, Koen Raemdonck, Kris Gevaert, Liu L, Marjana Brkic, Riet De Rycke, Roosmarijn E Vandenbroucke, Seehusen DA, Sriram Balusu, Stephan Stremersch, Valerie Vanhooren   +14 more
core   +3 more sources

Paclitaxel triggers molecular and cellular changes in the choroid plexus [PDF]

Frontiers in Pain Research
Paclitaxel is a widely used chemotherapeutic agent for treating various solid tumors. However, resulting neuropathic pain, often a lifelong side effect of paclitaxel, can limit dosing and compromise optimal treatment.
Alemeh Zamani, Parisa EmamiAref, Lucie Kubíčková, Klaudia Hašanová, Ondřej Šandor, Petr Dubový, Marek Joukal   +6 more
doaj   +2 more sources

Choroid plexus-mediated CSF secretion remains stable in aging rats via high and age-resistant metabolic activity [PDF]

Nature Communications
Our brain is bathed in cerebrospinal fluid (CSF) that is produced by the choroid plexus. CSF serves as a dispersion route for hormones and nutrients, and a conduit for waste clearance.
Sara D. Lolansen, Eszter O. Révész, Søren N. Andreassen, Marleen Trapp, Chiara Salio, Marco Sassoé-Pognetto, Jens Velde Andersen, Emil W. Westi, Trine L. Toft-Bertelsen, Jonathan H. Wardman, Anne-Kristine Meinild Lundby, Flemming Dela, Annarita Patrizi, Blanca I. Aldana, Nanna MacAulay   +14 more
doaj   +2 more sources