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Evidence for reduced choroid plexus volume in the aged brain [PDF]

open access: yesFluids and Barriers of the CNS
Background The choroid plexus plays an important role in brain homeostasis, including the active secretion of cerebrospinal fluid. Its function and structure have been reported to be affected by normal ageing. However, existing measures of choroid plexus
R. Youh   +7 more
doaj   +2 more sources

A probabilistic deep learning approach for choroid plexus segmentation in autism spectrum disorder [PDF]

open access: yesNPP-Digital Psychiatry and Neuroscience
The choroid plexus serves as the primary barrier between the brain’s blood and cerebrospinal fluid and mediates neuroimmune function. A subset of individuals with autism spectrum disorder (ASD) may exhibit morphological alterations of the choroid plexus.
Filippo Bargagna   +9 more
doaj   +2 more sources

Choroid plexus volume in brain disorders: a systematic review [PDF]

open access: yesFluids and Barriers of the CNS
Background The choroid plexus is a highly vascularized structure located in the lateral, third, and fourth ventricles of the brain. Recent studies suggest that volumetric changes in choroid plexus volume are associated with progression in various brain ...
Derya Tireli   +6 more
doaj   +2 more sources

Morphology of the murine choroid plexus: Attachment regions and spatial relation to the subarachnoid space

open access: yesFrontiers in Neuroanatomy, 2022
The choroid plexus has recently been identified as a possible migration route for peripheral immune cells into the central nervous system. For future investigation of this route, profound knowledge of the morphology of the murine choroid plexus is a ...
Theresa Greiner   +8 more
doaj   +1 more source

Choroid plexus epithelium and its role in neurological diseases

open access: yesFrontiers in Molecular Neuroscience, 2022
Choroid plexus epithelial cells can secrete cerebrospinal fluid into the ventricles, serving as the major structural basis of the selective barrier between the neurological system and blood in the brain.
Ruizhen Liu   +21 more
doaj   +1 more source

Choroid plexus APP regulates adult brain proliferation and animal behavior

open access: yesLife Science Alliance, 2021
Adult mouse choroid plexus shows elevated APP expression. sAPPα secreted into the CSF modulates neurogenic niche proliferation, whereas choroid plexus expression of fAD APP mutants leads to reduced niche proliferation, deficits in hippocampus synaptic ...
Karen Arnaud   +10 more
doaj   +1 more source

Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling

open access: yesFluids and Barriers of the CNS, 2020
Background The choroid plexus is a major contributor to the generation of cerebrospinal fluid (CSF) and the maintenance of its electrolyte and metabolite balance.
Li Zhao   +4 more
doaj   +1 more source

An extremely rare case of choroid plexus carcinoma in the third ventricle of an infant – Case report and review of the literature

open access: yesInterdisciplinary Neurosurgery, 2020
Background: Choroid plexus tumors are rare intraventricular tumors. Most of these tumors are benign choroid plexus papillomas. Choroid plexus carcinoma is the most malignant choroid plexus tumor and constitutes a small percentage of these tumors.
Amin Tavallaii   +3 more
doaj   +1 more source

Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice

open access: yesToxicology Reports, 2021
Sepsis-associated encephalopathy (SAE) is characterized as diffuse brain dysfunction in patients with excessive systemic inflammatory reaction to an infection.
Atsuyoshi Shimada, Sanae Hasegawa-Ishii
doaj   +1 more source

Targeting choroid plexus epithelium as a novel therapeutic strategy for hydrocephalus

open access: yesJournal of Neuroinflammation, 2022
The choroid plexus is a tissue located in the lateral ventricles of the brain and is composed mainly of choroid plexus epithelium cells. The main function is currently thought to be the secretion of cerebrospinal fluid and the regulation of its pH, and ...
Yijian Yang   +7 more
doaj   +1 more source

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