Results 41 to 50 of about 19,241 (174)
Fluids and Barriers of the CNS, 2023 Background Hydrocephalus constitutes a complex neurological condition of heterogeneous origin characterized by excessive cerebrospinal fluid (CSF) accumulation within the brain ventricles.
Sara Diana Lolansen +5 more
doaj +1 more source
Choroid Plexus Volume, Amyloid Burden, and Cognition in the Alzheimer's Disease Continuum. [PDF]
Aging DisAs a part of the glymphatic system, the choroid plexus (CP) is involved in the clearance of harmful metabolites from the brain. We investigated the association between CP volume (CPV), amyloid-β (Aβ) burden, and cognition in patients on the Alzheimer's disease (AD) continuum.
Jeong SH +8 more
europepmc +3 more sources
Giant Pediatric Supratentorial Tumor: Clinical Feature and Surgical Strategy
Frontiers in Pediatrics, 2022 PurposeTo analyze the clinical character of giant pediatric supratentorial tumor (GPST) and explore prognostic factors.Materials and MethodsWe analyzed the clinical data comprising of 35 cases of GPST from a single center between January 2015 and ...
Zhong-Ding Zhang +11 more
doaj +1 more source
Choroid plexus volume predicts expansion of chronic lesions and brain atrophy [PDF]
, 2022 Background and Objectives The expansion of long-standing multiple sclerosis (MS) lesions and an enlargement of choroid plexus are linked to chronic inflammation and microglial activation. In the current study, we investigated the association between plexus volume and subsequent lesion expansion in patients with ...
Samuel Klistorner +4 more
openaire +1 more source
Neurologia Medico-Chirurgica, 2023 Cerebrospinal fluid (CSF) production and absorption concept significantly changed in the early 2010s from “third circulation theory” and “classical bulk flow theory” to a whole new one as follows: First, CSF is mainly produced from interstitial fluid ...
Shigeki YAMADA, Mitsuhito MASE
doaj +1 more source
Choroid plexus volume is enlarged in long COVID and associated with cognitive and brain changes. [PDF]
Mol PsychiatryPatients with post-COVID condition (PCC) present with diverse symptoms which persist at long-term after SARS-CoV-2 infection. Among these symptoms, cognitive impairment is one of the most prevalent and has been related to brain structural and functional changes.
Diez-Cirarda M +15 more
europepmc +3 more sources
From Rigid to Soft Robotic Approaches for Neuroendoscopy
Advanced Robotics Research, EarlyView.Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday +3 more
wiley +1 more source
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
Advanced Science, EarlyView.Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen +7 more
wiley +1 more source
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source