Results 41 to 50 of about 16,711 (227)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Reproducibility in the identification of retinal positions on serial fundus photographs: Theory and limitations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Background Imaging of the retina is accompanied by distortions so that positions in fundus photographs cannot be linearly translated to positions in the retinal fundus. The purpose of this study was to describe an algorithm and evaluate its reproducibility in identifying points on the retina from their representation on serial fundus ...
Toke Bek, Giovanni Ometto
wiley   +1 more source

Optical Coherence Tomography: An Adjunctive Tool for Differentiating between Choroidal Melanoma and Metastasis

open access: yesJournal of Ophthalmology, 2016
Purpose. To investigate the value of optical coherence tomography (OCT) for differentiation between choroidal melanoma and metastasis based on characteristics of the anterior choroidal surface and the chorioretinal interface. Methods.
Vicktoria Vishnevskia-Dai   +5 more
doaj   +1 more source

c-FLIP and the NOXA/Mcl-1 axis participate in the synergistic effect of pemetrexed plus cisplatin in human choroidal melanoma cells.

open access: yesPLoS ONE, 2017
Choroidal melanoma is the most common primary malignant intraocular tumor, and very few effective therapies are available to treat it. Our study aimed to understand whether pemetrexed plus cisplatin exerts a beneficial synergistic effect in human ...
Xiaofei Zhao   +3 more
doaj   +1 more source

Pseudomelanoma: occult intraocular foreign body mimicking choroidal melanoma

open access: yesGMS Ophthalmology Cases, 2023
Purpose: To report an occult intraocular foreign body mimicking choroidal melanoma. Methods: Medical records and imagings of the patient were retrospectively reviewed.Case description: A 76-year-old male was referred to our ocular oncology clinic with a ...
Yılmaz Çebi, Aslıhan   +3 more
doaj   +1 more source

Heterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma. [PDF]

open access: yes, 2013
PurposeTo report on the heterogeneity of monosomy 3 in a fine needle aspiration biopsy obtained transsclerally from choroidal melanoma for prognosis.MethodsAll clinical records for patients who had been diagnosed with choroidal melanoma and underwent ...
Burgess, Barry L   +4 more
core   +2 more sources

Metastatic potential of small posterior uveal melanomas

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the prevalence of aggressive traits in small posterior uveal melanomas (UM). Methods This retrospective, multicentre cohort study included 804 patients with small posterior UM (≤9 mm in largest basal diameter, ≤3 mm in thickness) from centres in the UK, Germany, and Sweden.
Gustav Stålhammar   +9 more
wiley   +1 more source

Pseudomelanomas at a referral ocular oncology center in Brazil

open access: yesRevista Brasileira de Oftalmologia
Objective: To evaluate the epidemiological, clinical, and imaging profile of lesions that mimic choroidal melanoma. Methods: Retrospective study of medical records of suspected choroidal melanoma lesions referred to the Ocular Oncology Service from the ...
Viviane Kely Costa Guedes   +3 more
doaj   +1 more source

A diagnostic assessment of angioarchitectonics of choroidal melanoma

open access: yesРоссийский офтальмологический журнал, 2021
Purpose: to study angioarchitectonics of choroidal melanoma with varied biometric characteristics by comparing the results of indocyanine green angiography (IAG) and OCT angiography (OCTA).Material and methods.
I. E. Panova   +3 more
doaj   +1 more source

Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]

open access: yes, 2019
Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana   +6 more
core  

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